The incidence of metabolic disorders, as well as of neurodegenerative diseases—mainly the
sporadic forms of Alzheimer's and Parkinson's disease—are increasing worldwide. Notably …

Familial hypercholesterolemia (FH) is a common genetic cause of premature cardiovascular
disease (CVD). The reported prevalence rates for both heterozygous FH (HeFH) and …

Rabbits (Oryctolagus cuniculus) have been the very frequently used as animal models in the
study of human lipid metabolism and atherosclerosis, because they have similar lipoprotein …

Atherosclerosis (AS) manifested by lipid accumulation, extracellular matrix protein
deposition, and calcification in the intima and media of the large to medium size arteries …

Results This meta-analysis of 8 studies involving 317 patients with FH and 244 non-FH
individuals did not suggest a significantly altered PWV in FH patients versus controls …

Familial hypercholesterolemia (FH) is underdiagnosed and undertreated in a majority of the
low-and middle-income countries. FH registries could prove useful in bridging the …

Background The deeper understanding of the complex hereditary basis of familial
hypercholesterolemia (FH) has raised the rationale of genetic testing, which has been …

Background and aims Familial hypercholesterolemia (FH) is an autosomal dominant
disorder with paramount health impacts. However, less than 1% FH patients in Taiwan were …

Aim: This study aimed to elucidate the gene and lipid profiles of children clinically diagnosed
with familial hypercholesterolemia (FH). Methods: A total of 21 dyslipidemia-related …

Genetic variants in low-density lipoprotein receptor (LDLR) are known to cause familial
hypercholesterolemia (FH), occurring in up to 1 in 200 people (Youngblom E. et al. 1993 …