Adherence in hypertension: a review of prevalence, risk factors, impact, and management

M Burnier, BM Egan - Circulation research, 2019 - ahajournals.org
The global epidemic of hypertension is largely uncontrolled and hypertension remains the
leading cause of noncommunicable disease deaths worldwide. Suboptimal adherence …

Poor medication adherence in type 2 diabetes: recognizing the scope of the problem and its key contributors

WH Polonsky, RR Henry - Patient preference and adherence, 2016 - Taylor & Francis
At least 45% of patients with type 2 diabetes (T2D) fail to achieve adequate glycemic control
(HbA1c< 7%). One of the major contributing factors is poor medication adherence. Poor …

Medication adherence measures: an overview

WY Lam, P Fresco - BioMed research international, 2015 - Wiley Online Library
WHO reported that adherence among patients with chronic diseases averages only 50% in
developed countries. This is recognized as a significant public health issue, since …

Medication adherence and its impact on glycemic control in type 2 diabetes mellitus patients with comorbidity: A multicenter cross-sectional study in Northwest …

AK Sendekie, AK Netere, AE Kasahun, EA Belachew - PLoS One, 2022 - journals.plos.org
Background Medication nonadherence in patients with chronic diseases, particularly in type
2 diabetes mellitus (T2DM) with comorbidity, has continued to be the cause of treatment …

Exercise reduces ambulatory blood pressure in patients with hypertension: a systematic review and meta‐analysis of randomized controlled trials

G Saco‐Ledo, PL Valenzuela… - Journal of the …, 2020 - ahajournals.org
Background Although exercise training reduces office blood pressure (BP), scarcer
evidence is available on whether these benefits also apply to ambulatory blood pressure …

Current situation of medication adherence in hypertension

B Vrijens, S Antoniou, M Burnier… - Frontiers in …, 2017 - frontiersin.org
Despite increased awareness, poor adherence to treatments for chronic diseases remains a
global problem. Adherence issues are common in patients taking antihypertensive therapy …

Evidence-Based Guideline for the management of osteoporosis in men

NR Fuggle, C Beaudart, O Bruyère… - Nature Reviews …, 2024 - nature.com
Historically, osteoporosis has been viewed as a disease of women, with research, trials of
interventions and guidelines predominantly focused as such. It is apparent, however, that …

When and how can real world data analyses substitute for randomized controlled trials?

JM Franklin, S Schneeweiss - Clinical Pharmacology & …, 2017 - Wiley Online Library
Regulators consider randomized controlled trials (RCTs) as the gold standard for evaluating
the safety and effectiveness of medications, but their costs, duration, and limited …

Type 2 diabetes in the real world: the elusive nature of glycemic control

SV Edelman, WH Polonsky - Diabetes care, 2017 - diabetesjournals.org
Despite US Food and Drug Administration (FDA) approval of over 40 new treatment options
for type 2 diabetes since 2005, the latest data from the National Health and Nutrition …

An examination of the socio-demographic correlates of patient adherence to self-management behaviors and the mediating roles of health attitudes and self-efficacy …

Z **e, K Liu, C Or, J Chen, M Yan, H Wang - BMC Public Health, 2020 - Springer
Background Patients with coexisting type 2 diabetes and hypertension generally exhibit
poor adherence to self-management, which adversely affects their disease control …