A new chemical space was explored based on an indolizine-chalcone hybrid, which was
readily accessible by base-mediated aldol condensation of indolizine bearing a 7-acetyl …

A highly enantioselective conjugate addition of indolizine and its analogues with α, β-
unsaturated 2-acyl imidazoles has been developed. In the presence of 1.0 mol% of Δ-Rh1 …

An organocatalytic highly diastero-and enantioselective Friedel–Crafts conjugate addition of
indolizines to prochiral cyclopentenediones has been successfully developed. This …

Oxidation potential-guided electrochemical radical–radical cross-coupling reactions
between N-heteroarenes and sodium sulfinates have been established. Thus, simple cyclic …

We report herein a highly straightforward strategy for the synthesis of a new axially chiral 3-
arylindolizine scaffold via organocatalytic asymmetric arylation reactions of indolizines and p …

A catalytic enantioselective conjugate addition of indolizines to enones is described. The
chiral phosphoric acid (S)‐TRIP activates α, β‐unsaturated ketones, thereby promoting an …

A Brønsted acid-catalyzed C3-alkylation of indolizines has been established with different
electrophiles such as ortho-hydroxybenzyl alcohols, other precursors of para-quinone …

An atom economical and environmentally benign protocol has been developed for the
regioselective C (sp2)–H bond functionalization of indolizines. The acetic acid-catalyzed …

In connection with our continued research to generate new aza-fused heteroaromatic
chemical scaffolds, we developed a highly atom-economical three-component route to novel …

A straightforward synthesis of indolizines and pyrrolo [1, 2-a] pyrazines was performed
through a cascade condensation/cyclization/aromatization reaction of substituted 2-formyl-N …