Neutrophils, the most abundant human immune cells, are rapidly recruited to sites of
infection, where they fulfill their life-saving antimicrobial functions. While traditionally …

The complement system is deeply embedded in our physiology and immunity. Complement
activation generates a multitude of molecules that converge simultaneously on the …

IN contrast to sessile cell types, lymphocytes migrate through the vasculature to become
diffusely distributed in tissues or organized in lymphoid structures. A complex array of …

The cell wall is essential to nearly every aspect of the biology and pathogenicity of Candida
albicans. Although it was intially considered an almost inert cellular structure that protected …

Lymphocyte function-associated antigen 1 (LFA-1) is a leukocyte cell surface giycopmtein
that promotes intelrceiiuiar adhesion in immunoiogicai and inflammatory reactions. it is an …

We describe the isolation, characterization, and sequence of cDNA clones encoding one
subunit of the complex of membrane glycoproteins that forms part of the transmembrane …

While the leukocyte integrin lymphocyte function-associated antigen (LFA)-1 has been
demonstrated to bind intercellular adhesion molecule (ICAM)-1, results with the related Mac …

Leukocyte adhesion deficiency (LAD) is a recently recognized autosomal recessive trait
characterized by recurrent bacterial infections, impaired pus formation and wound healing …

The adherence of human neutrophils to human umbilical vein endothelial cells (HUVEC) is
partially dependent on the CD11/CD18 family of glycoproteins on the neutrophil and ICAM-1 …

For a cell to move forward it must convert chemical energy into mechanical propulsion.
Force produced by actin polymerization can generate traction across the plasma membrane …