As it is well known, messenger RNA has many regulatory regions along its sequence length.
One of them is the 5′ untranslated region (5'UTR), which itself contains many regulatory …

Long non-coding RNAs (lncRNAs) are emerging as a major class of gene products that
have central roles in cell and developmental biology. Natural antisense transcripts (NATs) …

Modern genome-scale methods that identify new genes, such as proteogenomics and
ribosome profiling, have revealed, to the surprise of many, that overlap in genes, open …

Antisense transcription (transcription from the opposite strand to a protein-coding or sense
strand) has been ascribed roles in gene regulation involving degradation of the …

Transcription of a gene usually ends at a regulated termination point, preventing the RNA-
polymerase from reading through the next gene. However, sporadic reports suggest that …

Mammalian genomes harbor a larger than expected number of complex loci, in which
multiple genes are coupled by shared transcribed regions in antisense orientation and/or by …

Suitable for advanced undergraduates and postgraduates, Understanding Bioinformatics
provides a definitive guide to this vibrant and evolving discipline. The book takes a …

In the more than one decade since the completion of the Human Genome Project, the
prevalence of non-protein-coding functional elements in the human genome has emerged …

The" immortal strand" hypothesis proposes that asymmetrically dividing stem cells
selectively retain chromosomes containing" old" DNA to prevent accumulation of mutations …

Overlap** genes in mammalian genomes are unexpected phenomena even though
hundreds of pairs of protein coding overlap** genes have been reported so far …