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Cellular and molecular mechanisms of skin wound healing
Wound healing is a complex process that involves the coordinated actions of many different
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …
Natural killer cell therapies
Natural killer (NK) cells are lymphocytes of the innate immune system. A key feature of NK
cells is their ability to recognize a wide range of cells in distress, particularly tumour cells …
cells is their ability to recognize a wide range of cells in distress, particularly tumour cells …
Gut-microbiota-derived metabolites maintain gut and systemic immune homeostasis
J Wang, N Zhu, X Su, Y Gao, R Yang - Cells, 2023 - mdpi.com
The gut microbiota, including bacteria, archaea, fungi, viruses and phages, inhabits the
gastrointestinal tract. This commensal microbiota can contribute to the regulation of host …
gastrointestinal tract. This commensal microbiota can contribute to the regulation of host …
Gut liver brain axis in diseases: the implications for therapeutic interventions
M Yan, S Man, B Sun, L Ma, L Guo, L Huang… - Signal transduction and …, 2023 - nature.com
Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …
TGF-β Regulation of T Cells
Transforming growth factor β (TGF-β) is a key cytokine regulating the development,
activation, proliferation, differentiation, and death of T cells. In CD4+ T cells, TGF-β maintains …
activation, proliferation, differentiation, and death of T cells. In CD4+ T cells, TGF-β maintains …
ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut
Microbial colonization of the mammalian intestine elicits inflammatory or tolerogenic T cell
responses, but the mechanisms controlling these distinct outcomes remain poorly …
responses, but the mechanisms controlling these distinct outcomes remain poorly …
[HTML][HTML] Gut microbiota-derived tryptophan metabolites maintain gut and systemic homeostasis
X Su, Y Gao, R Yang - Cells, 2022 - mdpi.com
Tryptophan is an essential amino acid from dietary proteins. It can be metabolized into
different metabolites in both the gut microbiota and tissue cells. Tryptophan metabolites such …
different metabolites in both the gut microbiota and tissue cells. Tryptophan metabolites such …
Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity
Immune cell dysfunction within the tumor microenvironment (TME) undermines the control of
cancer progression. Established tumors contain phenotypically distinct, tumor-specific …
cancer progression. Established tumors contain phenotypically distinct, tumor-specific …
Mucosal immune responses to infection and vaccination in the respiratory tract
The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …
NK cell-based cancer immunotherapy: from basic biology to clinical development
Natural killer (NK) cell is a specialized immune effector cell type that plays a critical role in
immune activation against abnormal cells. Different from events required for T cell activation …
immune activation against abnormal cells. Different from events required for T cell activation …