Anemia is quite frequently diagnosed in older individuals and is a key indicator of various
reactive and clonal conditions. Many underlying diseases, like myelodysplastic syndrome …

High blood glucose level (hyperglycemia) is a leading indicator of diabetes mellitus (DM).
Erythrocytes are the most abundant cells in the circulation and the first to perceive changes …

Eryptosis is a regulated cell death (RCD) of mature erythrocytes initially described as a
counterpart of apoptosis for enucleated cells. However, over the recent years, a growing …

Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Despite lacking the central apoptotic machinery, senescent or damaged RBCs can undergo
an unusual apoptosis-like cell death, termed eryptosis. This premature death can be caused …

The average lifespan of circulating erythrocytes usually exceeds hundred days. Prior to that,
however, erythrocytes may be exposed to oxidative stress in the circulation which could …

Human red blood cells (RBC) are highly differentiated cells that have lost all organelles and
most intracellular machineries during their maturation process. RBC are fundamental for the …

Diabetes Mellitus (DM) is a complex metabolic disorder associated with multiple
microvascular complications leading to nephropathy, retinopathy, and neuropathy. Mounting …

Many factors in the surrounding environment have been reported to influence erythrocyte
deformability. It is likely that some influences represent reversible changes in erythrocyte …

Background A strong correlation exists between type 2 diabetes mellitus (T2DM) and
cardiovascular disease (CVD), with CVD and the presence of atherosclerosis being the …