[HTML][HTML] Delivery systems for gene therapy

S Mali - Indian journal of human genetics, 2013 - ncbi.nlm.nih.gov
The structure of DNA was unraveled by Watson and Crick in 1953, and two decades later
Arber, Nathans and Smith discovered DNA restriction enzymes, which led to the rapid …

New gene therapy strategies for cancer treatment: a review of recent patents

R Ortiz, C Melguizo, J Prados… - Recent patents on …, 2012 - benthamdirect.com
Cancer is the second leading cause of death in the Western world. The limited successes of
available treatments for cancer mean that new strategies need to be developed. The …

The use of antibody modified liposomes loaded with AMO-1 to deliver oligonucleotides to ischemic myocardium for arrhythmia therapy

M Liu, M Li, S Sun, B Li, D Du, J Sun, F Cao, H Li, F Jia… - Biomaterials, 2014 - Elsevier
Abstract MicroRNA-1 (miR-1) has been found in cardiac and skeletal tissues. It is
overexpressed in ischemic cardiac tissues. Down-regulation of miR-1 could relieve …

[PDF][PDF] Gene therapy using bacterial vectors

P Celec, R Gardlik - Front Biosci, 2017 - researchgate.net
Bacteria can be used for gene therapy via two strategies–either by transfection of eukaryotic
host cells using bacteria–bactofection or by alternative gene therapy that does not alter the …

Omega-3 polyunsaturated fatty acids reduce vascular endothelial growth factor production and suppress endothelial wound repair

W Zhuang, G Wang, L Li, G Lin, Z Deng - Journal of cardiovascular …, 2013 - Springer
Long-chain polyunsaturated omega-3 fatty acids (n-3 PUFAs) such as eicosapentaenoic
acid (EPA) and docosahexaenoic acid (DHA) have diverse beneficial effects on …

A flavonoid component from Docynia delavayi (Franch.) Schneid represses transplanted H22 hepatoma growth and exhibits low toxic effect on tumor-bearing mice

X Zhao, G Shu, L Chen, X Mi, Z Mei, X Deng - Food and chemical …, 2012 - Elsevier
The fruit of Docynia delavayi (Franch.) Schneid is a kind of popular food in southwestern
areas of China. Additionally, its rhizome has been long used as a folk medicine in the …

Regulation of vascular endothelial cell polarization and migration by Hsp70/Hsp90-organizing protein

J Li, X Sun, Z Wang, L Chen, D Li, J Zhou, M Liu - PLoS One, 2012 - journals.plos.org
Hsp70/Hsp90-organizing protein (HOP) is a member of the co-chaperone family, which
directly binds to chaperones to regulate their activities. The participation of HOP in cell …

Angiogenesis-related microRNAs in colon cancer

L Hong, Y Han, Y Zhou, A Nita - Expert opinion on biological …, 2013 - Taylor & Francis
Introduction: Angiogenesis, for its fundamental role in cancer growth and metastasis, has
become an appealing target in cancer therapy. A number of angiogenesis-related …

[HTML][HTML] Gene therapy in oral cancer: A review

MS Kumar, KMK Masthan, NA Babu… - Journal of Clinical and …, 2013 - ncbi.nlm.nih.gov
Gene therapy is the use of DNA as an agent to treat disease. Gene therapy aims at the
insertion of a functional gene into the cells of a patient for the correction of an inborn error of …

Multifunctional delivery systems for cancer gene therapy

EM McErlean, CM McCrudden… - Gene therapy: Principles …, 2015 - books.google.com
This chapter examines key concepts with respect to cancer gene therapy and the current
issues with respect to non-viral delivery. The biological and molecular barriers that need to …