Breast cancer is a global cause for concern owing to its high incidence around the world.
The alarming increase in breast cancer cases emphasizes the management of disease at …

Cancer classification aims to provide an accurate diagnosis of the disease and prediction of
tumor behavior to facilitate oncologic decision making. Traditional breast cancer …

As the field of translational 'omics has progressed, refined classifiers at both genomic and
proteomic levels have emerged to decipher the heterogeneity of breast cancer in a clinically …

Triple negative breast cancer (TNBC) is a subtype of breast tumor lacking hormone
receptors expression and HER2 gene amplification and represents 24% of newly diagnosed …

Breast cancer is a complex disease encompassing multiple tumor entities, each
characterized by distinct morphology, behavior and clinical implications. Besides estrogen …

Breast cancer is a heterogeneous complex of diseases, a spectrum of many subtypes with
distinct biological features that lead to differences in response patterns to various treatment …

Most patients with triple negative breast cancer (TNBC) do not respond to anti-PD1/PDL1
immunotherapy, indicating the necessity to explore immune checkpoint targets. B7H3 is a …

The International Agency for Research on Cancer (IARC) has recently reported a 66%
increase in the global number of cancer deaths since 1960. In the US alone, about one in …

Breast cancer is the most common malignant disease in women worldwide. In recent
decades, earlier diagnosis and better adjuvant therapy have substantially improved patient …

Background The four intrinsic subtypes of breast cancer, defined by differential expression of
50 genes (PAM50), have been shown to be predictive of risk of recurrence and benefit of …