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Diagnostics and correction of batch effects in large‐scale proteomic studies: a tutorial
Advancements in mass spectrometry‐based proteomics have enabled experiments
encompassing hundreds of samples. While these large sample sets deliver much‐needed …
encompassing hundreds of samples. While these large sample sets deliver much‐needed …
Harmonization strategies for multicenter radiomics investigations
Carrying out large multicenter studies is one of the key goals to be achieved towards a faster
transfer of the radiomics approach in the clinical setting. This requires large-scale radiomics …
transfer of the radiomics approach in the clinical setting. This requires large-scale radiomics …
A guide to ComBat harmonization of imaging biomarkers in multicenter studies
The impact of PET image acquisition and reconstruction parameters on SUV measurements
or radiomic feature values is widely documented. This scanner effect is detrimental to the …
or radiomic feature values is widely documented. This scanner effect is detrimental to the …
Faecal microbiome-based machine learning for multi-class disease diagnosis
Systemic characterisation of the human faecal microbiome provides the opportunity to
develop non-invasive approaches in the diagnosis of a major human disease. However …
develop non-invasive approaches in the diagnosis of a major human disease. However …
[HTML][HTML] Genetic drivers of epigenetic and transcriptional variation in human immune cells
Characterizing the multifaceted contribution of genetic and epigenetic factors to disease
phenotypes is a major challenge in human genetics and medicine. We carried out high …
phenotypes is a major challenge in human genetics and medicine. We carried out high …
Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes
D Castel, C Philippe, R Calmon, L Le Dret… - Acta …, 2015 - Springer
Diffuse intrinsic pontine glioma (DIPG) is the most severe paediatric solid tumour, with no
significant therapeutic progress made in the past 50 years. Recent studies suggest that …
significant therapeutic progress made in the past 50 years. Recent studies suggest that …
Assessment of variability in the SOMAscan assay
SOMAscan is an aptamer-based proteomics assay capable of measuring 1,305 human
protein analytes in serum, plasma, and other biological matrices with high sensitivity and …
protein analytes in serum, plasma, and other biological matrices with high sensitivity and …
Transcriptional atlas of intestinal immune cells reveals that neuropeptide α-CGRP modulates group 2 innate lymphoid cell responses
Signaling abnormalities in immune responses in the small intestine can trigger chronic type
2 inflammation involving interaction of multiple immune cell types. To systematically …
2 inflammation involving interaction of multiple immune cell types. To systematically …
Performance comparison of modified ComBat for harmonization of radiomic features for multicenter studies
Multicenter studies are needed to demonstrate the clinical potential value of radiomics as a
prognostic tool. However, variability in scanner models, acquisition protocols and …
prognostic tool. However, variability in scanner models, acquisition protocols and …
ProteomicsDB: a multi-omics and multi-organism resource for life science research
Abstract ProteomicsDB (https://www. ProteomicsDB. org) started as a protein-centric in-
memory database for the exploration of large collections of quantitative mass spectrometry …
memory database for the exploration of large collections of quantitative mass spectrometry …