Designing of biologically active scaffolds with optimal characteristics is one of the key factors
for successful tissue engineering. Recently, hydrogels have received a considerable interest …

Hydrogels, due to their unique biocompatibility, flexible methods of synthesis, range of
constituents, and desirable physical characteristics, have been the material of choice for …

Injectable biomaterial-based treatment is a promising strategy to enhance tissue repair after
traumatic spinal cord injury (SCI) by bridging cavity spaces. However, there are limited …

The cystic cavity that develops following injuries to brain or spinal cord is a major obstacle
for tissue repair in central nervous system (CNS). Here we report that injection of imidazole …

Spinal cord injury (SCI) is a serious problem that primarily affects younger and middle-aged
adults at its onset. To date, no effective regenerative treatment has been developed. Over …

We report the ability to direct the differentiation pathway of neural progenitor cells (NPCs)
within hydrogels having tunable mechanical properties. By modifying the polymeric sugar …

As one of the most intractable neurological diseases, spinal cord injury (SCI) often leads to
permanent neurological impairment in patients. Unfortunately, due to the complex …

Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological
deficit and social and financial burdens. It is currently being managed symptomatically, with …

An injury to the spinal cord causes long-lasting loss of nervous tissue because endogenous
nervous tissue repair and regeneration at the site of injury is limited. We engineered an …

During the past decades, improving patient neurological recovery following spinal cord
injury (SCI) has remained a challenge. An effective treatment for SCI would not only reduce …