[HTML][HTML] European consensus statement on congenital hypogonadotropic hypogonadism—pathogenesis, diagnosis and treatment
Congenital hypogonadotropic hypogonadism (CHH) is a rare disorder caused by the
deficient production, secretion or action of gonadotropin-releasing hormone (GnRH), which …
deficient production, secretion or action of gonadotropin-releasing hormone (GnRH), which …
The kisspeptin-GnRH pathway in human reproductive health and disease
BACKGROUND The discovery of kisspeptin as key central regulator of GnRH secretion has
led to a new level of understanding of the neuroendocrine regulation of human reproduction …
led to a new level of understanding of the neuroendocrine regulation of human reproduction …
Functional hypothalamic amenorrhea: an endocrine society clinical practice guideline
Abstract Cosponsoring Associations: The American Society for Reproductive Medicine, the
European Society of Endocrinology, and the Pediatric Endocrine Society. This guideline was …
European Society of Endocrinology, and the Pediatric Endocrine Society. This guideline was …
Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders
BACKGROUND Kisspeptin is a key regulator of hypothalamic gonadotropin-releasing
hormone (GnRH) neurons and is essential for reproductive health. A specific kisspeptin …
hormone (GnRH) neurons and is essential for reproductive health. A specific kisspeptin …
[HTML][HTML] Physiology of GNRH and gonadotropin secretion
P Marques, K Skorupskaite, KS Rozario… - Endotext …, 2022 - ncbi.nlm.nih.gov
Gonadotropin hormone-releasing hormone (GnRH) is the key regulator of the reproductive
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins follicle …
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins follicle …
The emerging therapeutic potential of kisspeptin and neurokinin B
B Patel, K Koysombat, EG Mills, J Tsoutsouki… - Endocrine …, 2024 - academic.oup.com
Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …
Comprehensive review on kisspeptin and its role in reproductive disorders
Kisspeptin has recently emerged as a key regulator of the mammalian reproductive axis. It is
known that kisspeptin, acting centrally via the kisspeptin receptor, stimulates secretion of …
known that kisspeptin, acting centrally via the kisspeptin receptor, stimulates secretion of …
The relationship between gut and adipose hormones, and reproduction
BACKGROUND Reproductive function is tightly regulated by nutritional status. Indeed, it has
been well described that undernutrition or obesity can lead to subfertility or infertility in …
been well described that undernutrition or obesity can lead to subfertility or infertility in …
Current understanding of hypothalamic amenorrhoea
RE Roberts, L Farahani, L Webber… - … in endocrinology and …, 2020 - journals.sagepub.com
Hypothalamic amenorrhoea (HA) accounts for approximately 30% of cases of secondary
amenorrhoea in women of reproductive age. It is caused by deficient secretion of …
amenorrhoea in women of reproductive age. It is caused by deficient secretion of …
Neuroendocrine control by kisspeptins: role in metabolic regulation of fertility
The neurohormonal control of reproduction involves a hierarchical network of central and
peripheral signals in the hypothalamic–pituitary–gonadal (HPG) axis. Development and …
peripheral signals in the hypothalamic–pituitary–gonadal (HPG) axis. Development and …