Liposomes: Structure, composition, types, and clinical applications

H Nsairat, D Khater, U Sayed, F Odeh, A Al Bawab… - Heliyon, 2022 - cell.com
Liposomes are now considered the most commonly used nanocarriers for various potentially
active hydrophobic and hydrophilic molecules due to their high biocompatibility …

[HTML][HTML] Overview of dual-acting drug methotrexate in different neurological diseases, autoimmune pathologies and cancers

P Koźmiński, PK Halik, R Chesori… - International journal of …, 2020 - mdpi.com
Methotrexate, a structural analogue of folic acid, is one of the most effective and extensively
used drugs for treating many kinds of cancer or severe and resistant forms of autoimmune …

Nanoparticles: Synthesis, characteristics, and applications in analytical and other sciences

M Sajid, J Płotka-Wasylka - Microchemical Journal, 2020 - Elsevier
Nanoparticles (NPs) are widely employed in different research areas, ranging from
analytical chemistry and environmental science to medicine, the agriculture and …

[HTML][HTML] Recent advances in using liposomes for delivery of nucleic acid-based therapeutics

H Nsairat, W Alshaer, F Odeh, E Esawi, D Khater… - OpenNano, 2023 - Elsevier
Nucleic acid therapeutics are rapidly expanding because of recent advancements in
production and purification. This class of therapeutics may change the field of disease …

Intranasal delivery of targeted polyfunctional gold–iron oxide nanoparticles loaded with therapeutic microRNAs for combined theranostic multimodality imaging and …

UK Sukumar, RJC Bose, M Malhotra, HA Babikir… - Biomaterials, 2019 - Elsevier
The prognosis for glioblastoma (GBM) remains depressingly low. The biological barriers of
the brain present a major challenge to achieving adequate drug concentrations for GBM …

[HTML][HTML] Three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use: melittin, apamin and mastoparan

M Moreno, E Giralt - Toxins, 2015 - mdpi.com
While knowledge of the composition and mode of action of bee and wasp venoms dates
back 50 years, the therapeutic value of these toxins remains relatively unexploded. The …

Unravelling the in vivo dynamics of liposomes: Insights into biodistribution and cellular membrane interactions

S Paramshetti, M Angolkar, S Talath, RAM Osmani… - Life Sciences, 2024 - Elsevier
Liposomes, as a colloidal drug delivery system dating back to the 1960s, remain a focal
point of extensive research and stand as a highly efficient drug delivery method. The …

Nano carriers for drug transport across the blood–brain barrier

X Li, J Tsibouklis, T Weng, B Zhang, G Yin… - Journal of drug …, 2017 - Taylor & Francis
Effective therapy lies in achieving a therapeutic amount of drug to the proper site in the body
and then maintaining the desired drug concentration for a sufficient time interval to be …

BCLA CLEAR–Contact lens technologies of the future

L Jones, A Hui, CM Phan, ML Read, D Azar… - Contact lens and …, 2021 - Elsevier
Contact lenses in the future will likely have functions other than correction of refractive error.
Lenses designed to control the development of myopia are already commercially available …

Role of miRNAs in neurodegeneration: From disease cause to tools of biomarker discovery and therapeutics

B Roy, E Lee, T Li, M Rampersaud - Genes, 2022 - mdpi.com
Neurodegenerative diseases originate from neuronal loss in the central nervous system
(CNS). These debilitating diseases progress with age and have become common due to an …