Lysosomes are single membrane-bound organelles containing acid hydrolases responsible
for the degradation of cellular cargo and maintenance of cellular homeostasis. Lysosomes …

Autophagy is an intracellular catabolic self-cannibalism that eliminates dysfunctional
cytoplasmic cargos by the fusion of cargo-containing autophagosomes with lysosomes to …

The development and application of traditional drugs represented by small molecule
chemical drugs and biological agents, especially inhibitors, have become the mainstream …

Vitamin D regulates the pleiotropic effect to maintain cellular homeostasis and
epidemiological evidence establishes an association between vitamin D deficiency and …

Natural visible light is an electromagnetic wave composed of a spectrum of monochromatic
wavelengths, each with a characteristic color. Photons are the basic units of light, and their …

Respiratory syncytial virus (RSV) hijacks cholesterol or autophagy pathways to facilitate
optimal replication. However, our understanding of the associated molecular mechanisms …

Autophagy is a self-renewal mechanism that maintains homeostasis and can promote tissue
regeneration by regulating inflammation, reducing oxidative stress and promoting cell …

Secondary mutation, T790M, conferring tyrosine kinase inhibitors (TKIs) resistance beyond
oncogenic epidermal growth factor receptor (EGFR) mutations presents a challenging unmet …

Recent interest in the role of ascorbate in crucial metabolic processes is driven by the
growing number of medical reports that show beneficial effects of ascorbate …

Abstract Spinocerebellar ataxia type 6 (SCA6) is a rare disease that is characterized by
cerebellar dysfunction. Patients have progressive motor coordination impairment, and …