Peroxisome proliferator–activated receptor α (PPAR α) is a nuclear receptor of clinical
interest as a drug target in various metabolic disorders. PPAR α also exhibits marked anti …

Inflammatory bowel disease (IBD) is a chronic and relapsing inflammatory disease of the
gastrointestinal tract. Although the precise etiology of IBD remains incompletely understood …

The three branched-chain amino acids (BCAAs) are the most hydrophobic of the amino
acids and play crucial roles in determining the structures of globular proteins as well as the …

The peroxisome proliferator-activated receptor α (PPARα, or NR1C1) is a nuclear hormone
receptor activated by a structurally diverse array of synthetic chemicals known as …

Peroxisome proliferator-activated receptors (PPARs) are transcription factors that belong to
the superfamily of nuclear hormone receptors and regulate the expression of several genes …

Recent epidemiological studies highlight the key role of the type of consumed unsaturated
fatty acid and the development of ulcerative colitis (UC). We aimed to review the potential …

Understanding the biological impact of gene–nutrient interactions will provide a key insight
into the pathogenesis and progression of diet-related polygenic disorders. This review …

Cardiovascular disease (CVD) results from complex interactions between genetic and
environmental factors. The evidence supports that gene–environment interactions modulate …

The intestinal tract harbors diverse microorganisms, host‐and microbiota‐derived
metabolites, and potentially harmful dietary antigens. The epithelial barrier separates the …

Cholesterol metabolism is a well-defined responder to dietary intakes and a classic
biomarker of cardiovascular health. For this reason, circulating cholesterol levels have …