Abstract The 'one-size-fits-all'approach followed by conventional drug delivery platforms
often restricts its application in pharmaceutical industry, due to the incapability of adapting to …

Drug delivery to the posterior eye segment is an important challenge in ophthalmology,
because many diseases affect the retina and choroid leading to impaired vision or …

Delivery of drugs to the posterior eye is challenging, owing to anatomical and physiological
constrains of the eye. There is an increasing need for managing rapidly progressing …

Intravitreal administration is the method of choice in drug delivery to the retina and/or
choroid. Rabbit is the most commonly used animal species in intravitreal pharmacokinetics …

Intravitreal administration of anti-vascular endothelial growth factor (VEGF) antibodies has
become the standard treatment for Age-Related Macular Degeneration; however, the …

Intravitreal administration of drugs has raised a large interest during the last two decades
improving the treatment of infectious diseases of the posterior segment of the eye or …

The eye is a highly specialized organ that is subject to a huge range of pathology. Both local
and systemic disease may affect different anatomical regions of the eye. The least invasive …

Topical drug delivery to the posterior segment of the eye is a very complex challenge.
However, topical delivery is highly desired, to achieve an easy-to-use treatment option for …

Effective drug delivery to the retina still remains a challenge due to ocular elimination
mechanisms and complex barriers that selectively limit the entry of drugs into the eye. To …

The clinical therapy for retinal vascular diseases requires repeated intravitreal injections of
drugs owing to their short half-life, which imposes health and economic burdens on patients …