Hybrid Sterility, Genetic Conflict and Complex Speciation: Lessons From the Drosophila simulans Clade Species

DC Presgraves, CD Meiklejohn - Frontiers in genetics, 2021 - frontiersin.org
The three fruitfly species of the Drosophila simulans clade—D. simulans, D. mauritiana, and
D. sechellia—have served as important models in speciation genetics for over 40 years …

Proliferation and dissemination of killer meiotic drive loci

EC Lai, AA Vogan - Current opinion in genetics & development, 2023 - Elsevier
Highlights•Meiotic drive genes are frequently composed of gene families.•Transposable
elements can drive meiotic gene family expansion.•Meiotic drive genes rapidly diversify and …

Highly contiguous assemblies of 101 drosophilid genomes

BY Kim, JR Wang, DE Miller, O Barmina, E Delaney… - Elife, 2021 - elifesciences.org
Over 100 years of studies in Drosophila melanogaster and related species in the genus
Drosophila have facilitated key discoveries in genetics, genomics, and evolution. While high …

Low-input PacBio sequencing generates high-quality individual fly genomes and characterizes mutational processes

H Jia, S Tan, Y Cai, Y Guo, J Shen, Y Zhang… - Nature …, 2024 - nature.com
Long-read sequencing, exemplified by PacBio, revolutionizes genomics, overcoming
challenges like repetitive sequences. However, the high DNA requirement (> 1 µg) is …

Rapid evolution of piRNA clusters in the Drosophila melanogaster ovary

SP Srivastav, C Feschotte, AG Clark - Genome Research, 2024 - genome.cshlp.org
The piRNA pathway is a highly conserved mechanism to repress transposable element (TE)
activity in the animal germline via a specialized class of small RNAs called piwi-interacting …

In-Depth Satellitome Analyses of 37 Drosophila Species Illuminate Repetitive DNA Evolution in the Drosophila Genus

LG de Lima, FJ Ruiz-Ruano - Genome Biology and Evolution, 2022 - academic.oup.com
Abstract Satellite DNAs (SatDNA) are ubiquitously present in eukaryotic genomes and have
been recently associated with several biological roles. Understanding the evolution and …

Satellite DNA-mediated diversification of a sex-ratio meiotic drive gene family in Drosophila

CA Muirhead, DC Presgraves - Nature ecology & evolution, 2021 - nature.com
Sex chromosomes are susceptible to the evolution of selfish meiotic drive elements that bias
transmission and distort progeny sex ratios. Conflict between such sex-ratio drivers and the …