Recent advances in nanomaterial-based biosensor for periodontitis detection

MH Hooshiar, MA Moghaddam, M Kiarashi… - Journal of biological …, 2024 - Springer
Periodontitis, a chronic inflammatory condition caused by bacteria, often causes gradual
destruction of the components that support teeth, such as the alveolar bone, cementum …

Saliva sampling: Methods and devices. An overview

FG Bellagambi, T Lomonaco, P Salvo, F Vivaldi… - TrAC Trends in …, 2020 - Elsevier
The continuous exchange of chemicals with blood and the non-invasive collection make
saliva an interesting specimen for clinical applications, from the detection of biomarkers to …

[HTML][HTML] Salivary biomarkers and their application in the diagnosis and monitoring of the most common oral pathologies

L Melguizo-Rodríguez, VJ Costela-Ruiz… - International journal of …, 2020 - mdpi.com
Saliva is a highly versatile biological fluid that is easy to gather in a non-invasive manner—
and the results of its analysis complement clinical and histopathological findings in the …

Accuracy of periodontitis diagnosis obtained using multiple molecular biomarkers in oral fluids: A systematic review and meta‐analysis

T Blanco‐Pintos, A Regueira‐Iglesias… - Journal of clinical …, 2023 - Wiley Online Library
Aim To determine the accuracy of biomarker combinations in gingival crevicular fluid (GCF)
and saliva through meta‐analysis to diagnose periodontitis in systemically healthy subjects …

Diagnostic sensitivity and specificity of host‐derived salivary biomarkers in periodontal disease amongst adults: systematic review

S Kc, XZ Wang, JE Gallagher - Journal of clinical …, 2020 - Wiley Online Library
Objective To systematically assess the diagnostic value of host‐derived salivary biomarkers
based on their reported sensitivity and specificity in relation to clinical parameters of …

Realizing the clinical utility of saliva for monitoring oral diseases

JL Ebersole, H Hasturk, M Huber… - Periodontology …, 2024 - Wiley Online Library
In the era of personalized/precision health care, additional effort is being expended to
understand the biology and molecular mechanisms of disease processes. How these …

Predictive periodontitis: The most promising salivary biomarkers for early diagnosis of periodontitis

C Cafiero, G Spagnuolo, G Marenzi… - Journal of Clinical …, 2021 - mdpi.com
The primary cause of tooth loss in the industrialized world is periodontitis, a bacterial
anaerobic infection whose pathogenesis is characterized by composite immune response …

Therapeutic significance of β-glucuronidase activity and its inhibitors: A review

P Awolade, N Cele, N Kerru, L Gummidi… - European Journal of …, 2020 - Elsevier
The emergence of disease and dearth of effective pharmacological agents on most
therapeutic fronts, constitutes a major threat to global public health and man's existence …

Accuracy of single molecular biomarkers in saliva for the diagnosis of periodontitis: A systematic review and meta‐analysis

N Arias‐Bujanda, A Regueira‐Iglesias… - Journal of Clinical …, 2020 - Wiley Online Library
Aim To analyse, using a meta‐analytical approach, the diagnostic accuracy of single
molecular biomarkers in saliva for the detection of periodontitis in systemically healthy …

Saliva–a new opportunity for fluid biopsy

Z Huang, X Yang, Y Huang, Z Tang, Y Chen… - Clinical Chemistry and …, 2023 - degruyter.com
Saliva is a complex biological fluid with a variety of biomolecules, such as DNA, RNA,
proteins, metabolites and microbiota, which can be used for the screening and diagnosis of …