Multiple myeloma (MM) is typically exemplified by a desynchronized cytokine system with
increased levels of inflammatory cytokines. We focused on the contrast between …

The nuclear factor κB (NF-κB) system is critical for various biological functions in numerous
cell types, including the inflammatory response, cell proliferation, survival, differentiation …

Epithelial-mesenchymal heterogeneity implies that cells within the same tumor can exhibit
different phenotypes—epithelial, mesenchymal, or one or more hybrid epithelial …

Multiple myeloma (MM), an incurable plasma cell cancer, represents the second most
prevalent hematological malignancy. Deregulated activity of the nuclear factor kappaB (NF …

Obesity is a global pandemic that has been associated with the development of breast,
endometrial, large intestine, renal, esophageal, and pancreatic cancer. Obesity is also …

Highlights•Inflammatory genes are activated in a stimulus-type-specific and cell-type-specific
manner.•Deregulated inflammatory gene expressions have been linked to human …

One promising strategy for minimizing chemotherapeutic resistance in hepatocellular
carcinoma (HCC) is the use of effective chemosensitizers. We studied the complementary …

Multiple myeloma (MM) is the second-most-common hematologic malignancy and the most
frequent cancer to involve bone. MM bone disease (MMBD) has devastating consequences …

Simple Summary Tumor necrosis factor (TNF) and its closely related cytokine, lymphotoxin
alpha (LTα), are part of the TNF superfamily and exert their functions via both overlap** …

Glioblastoma (GBM) is the most aggressive malignant primary brain tumor characterized by
a highly heterogeneous and immunosuppressive tumor microenvironment (TME). The …