Trends in the development of miRNA bioinformatics tools

L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …

Bioinformatic tools for microRNA dissection

MM Akhtar, L Micolucci, MS Islam, F Olivieri… - Nucleic acids …, 2016 - academic.oup.com
Recently, microRNAs (miRNAs) have emerged as important elements of gene regulatory
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …

MiPred: classification of real and pseudo microRNA precursors using random forest prediction model with combined features

P Jiang, H Wu, W Wang, W Ma, X Sun… - Nucleic acids …, 2007 - academic.oup.com
To distinguish the real pre-miRNAs from other hairpin sequences with similar stem-loops
(pseudo pre-miRNAs), a hybrid feature which consists of local contiguous structure …

microRNA: a master regulator of cellular processes for bioengineering systems

W Sun, YS Julie Li, HD Huang… - Annual review of …, 2010 - annualreviews.org
microRNAs (miRNAs) are small RNAs 18 to 24 nucleotides in length that serve the pivotal
function of regulating gene expression. Instead of being translated into proteins, the mature …

miRanalyzer: a microRNA detection and analysis tool for next-generation sequencing experiments

M Hackenberg, M Sturm, D Langenberger… - Nucleic acids …, 2009 - academic.oup.com
Next-generation sequencing allows now the sequencing of small RNA molecules and the
estimation of their expression levels. Consequently, there will be a high demand of …

Emerging role of microRNAs in cardiovascular biology

MVG Latronico, D Catalucci, G Condorelli - Circulation research, 2007 - ahajournals.org
The heart is among the most conserved organs of the body and is susceptible to defects
more than any other organ. Heart malformations, in fact, occur in roughly 1% of newborns …

Computational approaches for microRNA studies: a review

L Li, J Xu, D Yang, X Tan, H Wang - Mammalian Genome, 2010 - Springer
MicroRNAs (miRNAs) are one class of tiny, endogenous RNAs that can regulate messenger
RNA (mRNA) expression by targeting homologous sequences in mRNAs. Their aberrant …

Discovery of microRNA–mRNA modules via population-based probabilistic learning

JG Joung, KB Hwang, JW Nam, SJ Kim… - …, 2007 - academic.oup.com
Abstract Motivation: MicroRNAs (miRNAs) and mRNAs constitute an important part of gene
regulatory networks, influencing diverse biological phenomena. Elucidating closely related …

An insect virus-encoded microRNA regulates viral replication

M Hussain, RJ Taft, S Asgari - Journal of virology, 2008 - journals.asm.org
MicroRNAs (miRNAs) are small (∼ 22 nucleotides) noncoding RNAs which play an
essential role in gene regulation and affect a wide range of processes, including …

MicroRNA detection and target prediction: integration of computational and experimental approaches

K Chaudhuri, R Chatterjee - DNA and cell biology, 2007 - liebertpub.com
In recent years, microRNAs (miRNAs), a class of 19–25 nucleotides noncoding RNAs, have
been shown to play a major role in gene regulation across a broad range of metazoans and …