The role of glial autophagy in Alzheimer's disease

A Litwiniuk, GR Juszczak, AM Stankiewicz… - Molecular …, 2023 - nature.com
Although Alzheimer's disease is the most pervasive neurodegenerative disorder, the
mechanism underlying its development is still not precisely understood. Available data …

Autophagy and stem cells: self-eating for self-renewal

NC Chang - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
Autophagy is a fundamental cell survival mechanism that allows cells to adapt to metabolic
stress through the degradation and recycling of intracellular components to generate …

Autophagy in neuronal development and plasticity

A Fleming, DC Rubinsztein - Trends in neurosciences, 2020 - cell.com
Autophagy is a highly conserved intracellular clearance pathway in which cytoplasmic
contents are trafficked to the lysosome for degradation. Within neurons, it helps to remove …

GSK3B induces autophagy by phosphorylating ULK1

HY Ryu, LE Kim, H Jeong, BK Yeo, JW Lee… - … & molecular medicine, 2021 - nature.com
Unc-51-like autophagy activating kinase 1 (ULK1), a mammalian homolog of the yeast
kinase Atg1, has an essential role in autophagy induction. In nutrient and growth factor …

[HTML][HTML] The role of autophagy in the metabolism and differentiation of stem cells

M Adelipour, LR Saleth, S Ghavami… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Autophagy is a very well-coordinated intracellular process that maintains cellular
homeostasis under basal conditions by removing unnecessary or dysfunctional components …

The contribution of astrocyte autophagy to systemic metabolism

A Ortiz-Rodriguez, MA Arevalo - International Journal of Molecular …, 2020 - mdpi.com
Autophagy is an essential mechanism to maintain cellular homeostasis. Besides its role in
controlling the quality of cytoplasmic components, it participates in nutrient obtaining and …

Autophagy in neural stem cells and glia for brain health and diseases

A Nagayach, C Wang - Neural Regeneration Research, 2024 - journals.lww.com
Autophagy is a multifaceted cellular process that not only maintains the homeostatic and
adaptive responses of the brain but is also dynamically involved in the regulation of neural …

Autophagy regulation combined with stem cell therapy for treatment of spinal cord injury

Y Shen, YP Wang, X Cheng, X Yang… - Neural Regeneration …, 2023 - journals.lww.com
Stem cells are a group of cells with unique self-renewal and differentiation abilities that have
great prospects in the repair of spinal cord injury. However, stem cell renewal and …

[HTML][HTML] Glial cell line-derived neurotrophic factor-overexpressing human neural stem/progenitor cells enhance therapeutic efficiency in rat with traumatic spinal cord …

K Hwang, K Jung, IS Kim, M Kim, J Han… - Experimental …, 2019 - ncbi.nlm.nih.gov
Spinal cord injury (SCI) causes axonal damage and demyelination, neural cell death, and
comprehensive tissue loss, resulting in devastating neurological dysfunction. Neural …

Autophagy promoted neural differentiation of human placenta-derived mesenchymal stem cells

A Sotthibundhu, P Muangchan, R Phonchai… - in vivo, 2021 - iv.iiarjournals.org
Background/Aim: Human placenta-derived mesenchymal stem cells (hPMSCs) are
multipotent and possess neurogenicity. Numerous studies have shown that Notch inhibition …