Processes involving lipases in obtaining active pharmaceutical ingredients (APIs) are crucial
to increase the sustainability of the industry. Despite their lower production cost, microbial …

Novozym 435 (N435) is a commercially available immobilized lipase produced by
Novozymes. It is based on immobilization via interfacial activation of lipase B from Candida …

Biocatalysis is a green and sustainable process for synthesizing chiral organic building
blocks and active pharmaceutical ingredients (API). United Nations' Sustainable …

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) introduced in the 1960s and
widely used as an analgesic, anti-inflammatory, and antipyretic. In its acid form, the solubility …

This study explored for the first time the use of a flow-packed bed bioreactor for producing 5-
acetyl-hydroxymethylfurfural (5-acetyl-HMF) and semicontinuous liquid–liquid extraction …

Transesterification is one of the paramount chemical reactions in organic synthesis and is
broadly used to synthesize the biologically and pharmacologically active heterocycles of …

In this paper, an enzymatic route for synthesizing phenolic glycoside azelaic acid esters was
successfully set up via lipase-catalyzed esterification and transesterification. Among the …

This work studied the enantioselective resolution of 2-arylpropionic acid derivatives
employing immobilization of lipase produced by Bacillus subtilis strain Kakrayal_1 (BSK-L) …

It is not clear how the amino acid composition of the X sites in GXSXG domain affects the
properties of the lipase. To address this, saturation mutation at these sites of Penicillium …

Lipases are known for their high catalytic activity, unique substrate selectivity, and acyl chain
length specificity. To investigate the acyl chain length specificity and catalytic properties of …