The neural bases of emotion regulation

A Etkin, C Büchel, JJ Gross - Nature reviews neuroscience, 2015 - nature.com
Emotions are powerful determinants of behaviour, thought and experience, and they may be
regulated in various ways. Neuroimaging studies have implicated several brain regions in …

The multifaceted role of the ventromedial prefrontal cortex in emotion, decision making, social cognition, and psychopathology

J Hiser, M Koenigs - Biological psychiatry, 2018 - Elsevier
The ventromedial prefrontal cortex (vmPFC) has been implicated in a variety of social,
cognitive, and affective functions that are commonly disrupted in mental illness. In this …

Maximizing exposure therapy: An inhibitory learning approach

MG Craske, M Treanor, CC Conway, T Zbozinek… - Behaviour research and …, 2014 - Elsevier
Exposure therapy is an effective approach for treating anxiety disorders, although a
substantial number of individuals fail to benefit or experience a return of fear after treatment …

Obsessive-compulsive disorder: puzzles and prospects

TW Robbins, MM Vaghi, P Banca - Neuron, 2019 - cell.com
Obsessive-compulsive disorder is a severe and disabling psychiatric disorder that presents
several challenges for neuroscience. Recent advances in its genetic and developmental …

Updated meta‐analysis of classical fear conditioning in the anxiety disorders

P Duits, DC Cath, S Lissek, JJ Hox… - Depression and …, 2015 - Wiley Online Library
The aim of the current study was twofold:(1) to systematically examine differences in fear
conditioning between anxiety patients and healthy controls using meta‐analytic methods …

Neural signatures of human fear conditioning: an updated and extended meta-analysis of fMRI studies

MA Fullana, BJ Harrison, C Soriano-Mas… - Molecular …, 2016 - nature.com
Classical Pavlovian fear conditioning remains the most widely employed experimental
model of fear and anxiety, and continues to inform contemporary pathophysiological …

Stress, glucocorticoids and memory: implications for treating fear-related disorders

D de Quervain, L Schwabe… - Nature Reviews …, 2017 - nature.com
Glucocorticoid stress hormones are crucially involved in modulating mnemonic processing
of emotionally arousing experiences. They enhance the consolidation of new memories …

Harmonizing the neurobiology and treatment of obsessive-compulsive disorder

WK Goodman, EA Storch… - American Journal of …, 2021 - Am Psychiatric Assoc
Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling
disorder. The only established first-line treatments for OCD are exposure and response …

From Pavlov to PTSD: the extinction of conditioned fear in rodents, humans, and anxiety disorders

MB VanElzakker, MK Dahlgren, FC Davis… - Neurobiology of learning …, 2014 - Elsevier
Abstract Nearly 100 years ago, Ivan Pavlov demonstrated that dogs could learn to use a
neutral cue to predict a biologically relevant event: after repeated predictive pairings …

The role of associative fear and avoidance learning in anxiety disorders: Gaps and directions for future research

A Pittig, M Treanor, RT LeBeau, MG Craske - … & Biobehavioral Reviews, 2018 - Elsevier
Anxiety disorders are the most common mental disorders and are often chronic and
disabling. Although exposure-based treatments are effective, a substantial number of …