Over the last 50 years, the concept of stress has evolved significantly, and our
understanding of the underlying neurobiology has expanded dramatically. Rather than …

Background Sleep disturbance is associated with inflammatory disease risk and all-cause
mortality. Here, we assess global evidence linking sleep disturbance, sleep duration, and …

COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has
been often characterized as a respiratory disease. However, it is increasingly being …

Sleep disturbances including insomnia independently contribute to risk of inflammatory
disorders and major depressive disorder. This review and overview provides an integrated …

Background Studies investigating inflammatory markers in post-traumatic stress disorder
(PTSD) have yielded mixed results. The aim of our study was to compare concentrations of …

Children who experience chronic stressors are vulnerable to emotional and physical health
problems across the lifespan. This phenomenon raises questions for scientists and …

As the field begins to test the concept of a" preclinical" stage of neurodegenerative disease,
when the pathophysiological process has begun in the brain, but clinical symptoms are not …

Sleep has a critical role in promoting health. Research over the past decade has
documented that sleep disturbance has a powerful influence on the risk of infectious …

Inflammation is a physiological process that repairs tissues in response to endogenous or
exogenous aggressions. Nevertheless, a chronic state of inflammation may have detrimental …

Stress is a state of the mind, involving both brain and body as well as their interactions; it
differs among individuals and reflects not only major life events but also the conflicts and …