Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets
The arachidonic acid (AA) pathway plays a key role in cardiovascular biology,
carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified …
carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified …
Neuroinflammation: friend and foe for ischemic stroke
Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …
perspective with the emergence of new ideas on neurodegeneration. The concept that …
[HTML][HTML] Synopsis of arachidonic acid metabolism: A review
VS Hanna, EAA Hafez - Journal of advanced research, 2018 - Elsevier
Abstract Arachidonic acid (AA), a 20 carbon chain polyunsaturated fatty acid with 4 double
bonds, is an integral constituent of biological cell membrane, conferring it with fluidity and …
bonds, is an integral constituent of biological cell membrane, conferring it with fluidity and …
Home as the new frontier for the treatment of COVID-19: the case for anti-inflammatory agents
N Perico, M Cortinovis, F Suter… - The Lancet Infectious …, 2023 - thelancet.com
Summary COVID-19, caused by SARS-CoV-2, is characterised by a broad spectrum of
symptom severity that requires varying amounts of care according to the different stages of …
symptom severity that requires varying amounts of care according to the different stages of …
The cellular and molecular basis of major depressive disorder: towards a unified model for understanding clinical depression
E Pitsillou, SM Bresnehan, EA Kagarakis… - Molecular biology …, 2020 - Springer
Major depressive disorder (MDD) is considered a serious public health issue that adversely
impacts an individual's quality of life and contributes significantly to the global burden of …
impacts an individual's quality of life and contributes significantly to the global burden of …
Regulation of immune responses by prostaglandin E2
P Kalinski - The Journal of Immunology, 2012 - journals.aai.org
PGE 2, an essential homeostatic factor, is also a key mediator of immunopathology in
chronic infections and cancer. The impact of PGE 2 reflects the balance between its …
chronic infections and cancer. The impact of PGE 2 reflects the balance between its …
[HTML][HTML] Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis
Cellular senescence is a stress or damage response that causes a permanent proliferative
arrest and secretion of numerous factors with potent biological activities. This senescence …
arrest and secretion of numerous factors with potent biological activities. This senescence …
Potential of curcumin in skin disorders
Curcumin is a compound isolated from turmeric, a plant known for its medicinal use.
Recently, there is a growing interest in the medical community in identifying novel, low-cost …
Recently, there is a growing interest in the medical community in identifying novel, low-cost …
Health implications of high dietary omega‐6 polyunsaturated fatty acids
Omega‐6 (n‐6) polyunsaturated fatty acids (PUFA)(eg, arachidonic acid (AA)) and omega‐3
(n‐3) PUFA (eg, eicosapentaenoic acid (EPA)) are precursors to potent lipid mediator …
(n‐3) PUFA (eg, eicosapentaenoic acid (EPA)) are precursors to potent lipid mediator …
Platelet signaling and disease: targeted therapy for thrombosis and other related diseases
Platelets are essential for clotting in the blood and maintenance of normal hemostasis.
Under pathologic conditions such as atherosclerosis, vascular injury often results in …
Under pathologic conditions such as atherosclerosis, vascular injury often results in …