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Network pharmacology, a promising approach to reveal the pharmacology mechanism of Chinese medicine formula
L Zhao, H Zhang, N Li, J Chen, H Xu, Y Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Network pharmacology is a new discipline based on
systems biology theory, biological system network analysis, and multi-target drug molecule …
systems biology theory, biological system network analysis, and multi-target drug molecule …
Integration strategy of network pharmacology in Traditional Chinese Medicine: a narrative review
WU Jiashuo, F ZHANG… - Journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Traditional Chinese Medicine (TCM) has been extensively used as a mainstay for treating
various pathologies. Combing the pharmacology and systems biology approaches, the …
various pathologies. Combing the pharmacology and systems biology approaches, the …
A deep learning method for predicting metabolite–disease associations via graph neural network
F Sun, J Sun, Q Zhao - Briefings in bioinformatics, 2022 - academic.oup.com
Metabolism is the process by which an organism continuously replaces old substances with
new substances. It plays an important role in maintaining human life, body growth and …
new substances. It plays an important role in maintaining human life, body growth and …
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
Behaviors and disorders related to self-regulation, such as substance use, antisocial
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …
Inhibition of S6K lowers age-related inflammation and increases lifespan through the endolysosomal system
Suppression of target of rapamycin complex 1 (TORC1) by rapamycin ameliorates aging in
diverse species. S6 kinase (S6K) is an essential mediator, but the mechanisms involved are …
diverse species. S6 kinase (S6K) is an essential mediator, but the mechanisms involved are …
Network pharmacology databases for traditional Chinese medicine: review and assessment
The research field of systems biology has greatly advanced and, as a result, the concept of
network pharmacology has been developed. This advancement, in turn, has shifted the …
network pharmacology has been developed. This advancement, in turn, has shifted the …
Review of drug repositioning approaches and resources
Drug discovery is a time-consuming, high-investment, and high-risk process in traditional
drug development. Drug repositioning has become a popular strategy in recent years …
drug development. Drug repositioning has become a popular strategy in recent years …
OmicsNet 2.0: a web-based platform for multi-omics integration and network visual analytics
Researchers are increasingly seeking to interpret molecular data within a multi-omics
context to gain a more comprehensive picture of their study system. OmicsNet (www …
context to gain a more comprehensive picture of their study system. OmicsNet (www …
Network propagation: a universal amplifier of genetic associations
Biological networks are powerful resources for the discovery of genes and genetic modules
that drive disease. Fundamental to network analysis is the concept that genes underlying the …
that drive disease. Fundamental to network analysis is the concept that genes underlying the …
MDHGI: matrix decomposition and heterogeneous graph inference for miRNA-disease association prediction
Recently, a growing number of biological research and scientific experiments have
demonstrated that microRNA (miRNA) affects the development of human complex diseases …
demonstrated that microRNA (miRNA) affects the development of human complex diseases …