Activation of hepatic stellate cells (HSCs) plays a critical role in liver fibrosis. However, the
molecular basis for HSC activation remains poorly understood. Herein, we demonstrate that …

Inositol polyphosphate-5-phosphatase E (INPP5E) is a 5-phosphatase critically involved in
diverse physiological processes, including embryonic development, neurological function …

Over 94 million domestic cats are susceptible to cancers and other common and rare
diseases. Whole exome sequencing (WES) is a proven strategy to study these disease …

A female Lagotto Romagnolo dog with polycystic kidney disease (PKD) and her progeny,
including PKD-affected offspring, were studied. All affected dogs appeared clinically …

OBJECTIVE To characterize the association between peritoneopericardial diaphragmatic
hernia (PPDH) or congenital central diaphragmatic hernia (CCDH) and ductal plate …

Nephron progenitors (NPs) and nephrogenesis have been extensively studied in mice and
humans and have provided insights into the mechanisms of renal development, disease and …

Renal dysplasia (RD) is a complex congenital disease characterised by abnormal
differentiation of renal tissue (Greco, 2001). Several forms of inherited RD have been …

Over 94 million domestic cats are susceptible to cancers and other common and rare
diseases. While cancer treatment in cats increasingly mirrors that available in humans …

This patient presented to the Emergency Service for evaluation of a cough of 1-week
duration that was unresponsive to Baytril and Torbutrol. His cough became acutely worse, at …

Over 94 million domestic cats are considered pets, who, as our companions, are also 23
susceptible to cancers, common and rare diseases. Whole exome sequencing (WES) is 24 a …