Next generation gold drugs and probes: chemistry and biomedical applications
The gold drugs, gold sodium thiomalate (Myocrisin), aurothioglucose (Solganal), and the
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …
Gold complexes in anticancer therapy: From new design principles to particle‐based delivery systems
The discovery of the medicinal properties of gold complexes has fuelled the design and
synthesis of new anticancer metallodrugs, which have received special attention due to their …
synthesis of new anticancer metallodrugs, which have received special attention due to their …
New trends for metal complexes with anticancer activity
PCA Bruijnincx, PJ Sadler - Current opinion in chemical biology, 2008 - Elsevier
Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design
of new drugs. This has, for instance, led to the clinical application of chemotherapeutic …
of new drugs. This has, for instance, led to the clinical application of chemotherapeutic …
[BOOK][B] Bioinorganic Chemistry--Inorganic Elements in the Chemistry of Life: An Introduction and Guide
W Kaim, B Schwederski, A Klein - 2013 - books.google.com
The field of Bioinorganic Chemistry has grown significantly in recent years; now one of the
major sub-disciplines of Inorganic Chemistry, it has also pervaded other areas of the life …
major sub-disciplines of Inorganic Chemistry, it has also pervaded other areas of the life …
Stable cyclic carbenes and related species beyond diaminocarbenes
M Melaimi, M Soleilhavoup… - Angewandte Chemie …, 2010 - Wiley Online Library
The success of homogeneous catalysis can be attributed largely to the development of a
diverse range of ligand frameworks that have been used to tune the behavior of various …
diverse range of ligand frameworks that have been used to tune the behavior of various …
Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs
W Liu, R Gust - Chemical Society Reviews, 2013 - pubs.rsc.org
The discovery of cisplatin's antitumor activity in 1969 prompted the search for novel metal-
containing complexes as potential anticancer drugs. Among these novel complexes, metal N …
containing complexes as potential anticancer drugs. Among these novel complexes, metal N …
Coinage Metal−N-Heterocyclic Carbene Complexes
JCY Lin, RTW Huang, CS Lee, A Bhattacharyya… - Chemical …, 2009 - ACS Publications
An N-heterocyclic carbene (NHC) contains a carbene carbon incorporated in a nitrogen-
containing heterocycle, presumably reactive and difficult to isolate. 1 The first isolation of …
containing heterocycle, presumably reactive and difficult to isolate. 1 The first isolation of …
The Medicinal applications of imidazolium carbene− metal complexes
Ofele and Wanzlick reported the synthesis of the first N-heterocyclic carbene (NHC)-metal
complexes in 1968. 1, 2 The isolation of the first free carbene by Arduengo in 1991 set the …
complexes in 1968. 1, 2 The isolation of the first free carbene by Arduengo in 1991 set the …
On the medicinal chemistry of gold complexes as anticancer drugs
I Ott - Coordination Chemistry Reviews, 2009 - Elsevier
Metal complexes have shown interesting preclinical and clinical results as antitumor drugs
and platinum compounds are well established in current cancer chemotherapy. However …
and platinum compounds are well established in current cancer chemotherapy. However …
Beyond catalysis: N-heterocyclic carbene complexes as components for medicinal, luminescent, and functional materials applications
L Mercs, M Albrecht - Chemical Society Reviews, 2010 - pubs.rsc.org
This tutorial review compiles the advances that have been achieved in using transition metal
complexes containing N-heterocyclic carbene ligands as components for materials …
complexes containing N-heterocyclic carbene ligands as components for materials …