Applications of phyto-nanotechnology for the treatment of neurodegenerative disorders
The strategies involved in the development of therapeutics for neurodegenerative disorders
are very complex and challenging due to the existence of the blood-brain barrier (BBB), a …
are very complex and challenging due to the existence of the blood-brain barrier (BBB), a …
Recent advances on the improvement of quercetin bioavailability
Background Natural antioxidants, such as polyphenols, are finding increasing application in
functional foods designed to improve human health, wellbeing, and performance. Quercetin …
functional foods designed to improve human health, wellbeing, and performance. Quercetin …
Relationship between amyloid-β deposition and blood–brain barrier dysfunction in Alzheimer's disease
D Wang, F Chen, Z Han, Z Yin, X Ge… - Frontiers in Cellular …, 2021 - frontiersin.org
Amyloid-β (Aβ) is the predominant pathologic protein in Alzheimer's disease (AD). The
production and deposition of Aβ are important factors affecting AD progression and …
production and deposition of Aβ are important factors affecting AD progression and …
Neuropharmacological effects of quercetin: a literature-based review
Quercetin (QUR) is a natural bioactive flavonoid that has been lately very studied for its
beneficial properties in many pathologies. Its neuroprotective effects have been …
beneficial properties in many pathologies. Its neuroprotective effects have been …
Antioxidant therapy in oxidative stress-induced neurodegenerative diseases: Role of nanoparticle-based drug delivery systems in clinical translation
Free radicals are formed as a part of normal metabolic activities but are neutralized by the
endogenous antioxidants present in cells/tissue, thus maintaining the redox balance. This …
endogenous antioxidants present in cells/tissue, thus maintaining the redox balance. This …
[HTML][HTML] Surface-modified lipid nanocarriers for crossing the blood-brain barrier (BBB): A current overview of active targeting in brain diseases
MI Teixeira, CM Lopes, MH Amaral, PC Costa - Colloids and Surfaces B …, 2023 - Elsevier
The blood-brain barrier (BBB) restricts the access of therapeutic agents to the brain,
complicating the treatment of neurological diseases, such as Alzheimer's disease (AD) …
complicating the treatment of neurological diseases, such as Alzheimer's disease (AD) …
Improving drug delivery for Alzheimer's disease through nose-to-brain delivery using nanoemulsions, nanostructured lipid carriers (NLC) and in situ hydrogels
Current treatments for Alzheimer's disease (AD) attenuate the progression of symptoms and
aim to improve the patient's quality of life. Licensed medicines are mostly for oral …
aim to improve the patient's quality of life. Licensed medicines are mostly for oral …
Nanomedicine-based technologies and novel biomarkers for the diagnosis and treatment of Alzheimer's disease: from current to future challenges
Increasing life expectancy has led to an aging population, which has consequently
increased the prevalence of dementia. Alzheimer's disease (AD), the most common form of …
increased the prevalence of dementia. Alzheimer's disease (AD), the most common form of …
Nanoformulations to enhance the bioavailability and physiological functions of polyphenols
B Yang, Y Dong, F Wang, Y Zhang - Molecules, 2020 - mdpi.com
Polyphenols are micronutrients that are widely present in human daily diets. Numerous
studies have demonstrated their potential as antioxidants and anti-inflammatory agents, and …
studies have demonstrated their potential as antioxidants and anti-inflammatory agents, and …
Graphene quantum dots as a potential diagnostic and therapeutic tool for the management of Alzheimer's disease
Alzheimer's disease (AD) is one of the most common forms of dementia, affecting more than
50 million people globally. The onset of AD is linked to age, smoking, obesity …
50 million people globally. The onset of AD is linked to age, smoking, obesity …