Consequences of ionizing radiation exposure to the cardiovascular system
Ionizing radiation is widely used in various industrial and medical applications, resulting in
increased exposure for certain populations. Lessons from radiation accidents and …
increased exposure for certain populations. Lessons from radiation accidents and …
Targeting the redox system for cardiovascular regeneration in aging
Cardiovascular aging presents a formidable challenge, as the aging process can lead to
reduced cardiac function and heightened susceptibility to cardiovascular diseases …
reduced cardiac function and heightened susceptibility to cardiovascular diseases …
Glutamine metabolism regulates endothelial to hematopoietic transition and hematopoietic lineage specification
During hematopoietic development, definitive hematopoietic cells are derived from
hemogenic endothelial (HE) cells through a process known as endothelial to hematopoietic …
hemogenic endothelial (HE) cells through a process known as endothelial to hematopoietic …
Modelling Metabolic Shifts during Cardiomyocyte Differentiation, Iron Deficiency and Transferrin Rescue Using Human Pluripotent Stem Cells
Cardiomyocytes rely on specialised metabolism to meet the high energy demand of the
heart. During heart development, metabolism matures and shifts from the predominant …
heart. During heart development, metabolism matures and shifts from the predominant …
Perspective: Pathological transdifferentiation—a novel therapeutic target for cardiovascular diseases and chronic inflammation
Pathological transdifferentiation, where differentiated cells aberrantly transform into other
cell types that exacerbate disease rather than promote healing, represents a novel and …
cell types that exacerbate disease rather than promote healing, represents a novel and …
Can we stop one heart from breaking: triumphs and challenges in cardiac reprogramming
Highlights•Innovations improve induced cardiomyocyte reprogramming efficiency and
maturation.•Optimized strategies induce cardiomyocyte proliferation and cardiac progenitor …
maturation.•Optimized strategies induce cardiomyocyte proliferation and cardiac progenitor …
Next-generation direct reprogramming
R Keshri, D Detraux, A Phal, C McCurdy… - Frontiers in Cell and …, 2024 - frontiersin.org
Tissue repair is significantly compromised in the aging human body resulting in critical
disease conditions (such as myocardial infarction or Alzheimer's disease) and imposing a …
disease conditions (such as myocardial infarction or Alzheimer's disease) and imposing a …
Administration of stem cells against cardiovascular diseases with a focus on molecular mechanisms: Current knowledge and prospects
Cardiovascular diseases (CVDs) are a serious global concern for public and human health.
Despite the emergence of significant therapeutic advances, it is still the leading cause of …
Despite the emergence of significant therapeutic advances, it is still the leading cause of …
Cardiac reprogramming via chromatin remodeling by CRISPR activation
Cardiovascular progenitor cells (CPCs) are the resident cells in the heart that can generate
different cardiovascular cells, such as cardiomyocytes (CMs), smooth muscle cells (SMCs) …
different cardiovascular cells, such as cardiomyocytes (CMs), smooth muscle cells (SMCs) …