Neuropathic pain

L Colloca, T Ludman, D Bouhassira, R Baron… - Nature reviews Disease …, 2017 - nature.com
Neuropathic pain is caused by a lesion or disease of the somatosensory system, including
peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7–10% of the …

Challenges of neuropathic pain: focus on diabetic neuropathy

DC Rosenberger, V Blechschmidt… - Journal of Neural …, 2020 - Springer
Neuropathic pain is a frequent condition caused by a lesion or disease of the central or
peripheral somatosensory nervous system. A frequent cause of peripheral neuropathic pain …

Painful and non-painful diabetic neuropathy, diagnostic challenges and implications for future management

TS Jensen, P Karlsson, SS Gylfadottir, ST Andersen… - Brain, 2021 - academic.oup.com
Peripheral neuropathy is one of the most common complications of both type 1 and type 2
diabetes. Up to half of patients with diabetes develop neuropathy during the course of their …

Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms

TS Jensen, NB Finnerup - The Lancet Neurology, 2014 - thelancet.com
Allodynia (pain due to a stimulus that does not usually provoke pain) and hyperalgesia
(increased pain from a stimulus that usually provokes pain) are prominent symptoms in …

Neuropathic pain: principles of diagnosis and treatment

I Gilron, R Baron, T Jensen - Mayo clinic proceedings, 2015 - Elsevier
Neuropathic pain is caused by disease or injury of the nervous system and includes various
chronic conditions that, together, affect up to 8% of the population. A substantial body of …

The effect of oxcarbazepine in peripheral neuropathic pain depends on pain phenotype: a randomised, double-blind, placebo-controlled phenotype-stratified study

DT Demant, K Lund, J Vollert, C Maier, M Segerdahl… - PAIN®, 2014 - Elsevier
In neuropathic pain it has been suggested that pain phenotype based on putative pain
mechanisms may predict response to treatment. This was a randomised, double-blind …

Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

NB Finnerup, N Attal, S Haroutounian… - The Lancet …, 2015 - thelancet.com
Background New drug treatments, clinical trials, and standards of quality for assessment of
evidence justify an update of evidence-based recommendations for the pharmacological …

A review of neuropathic pain: from guidelines to clinical practice

G Cruccu, A Truini - Pain and therapy, 2017 - Springer
Neuropathic pain is a chronic condition representing a significant burden for patients,
society, and healthcare systems. The prevalence of neuropathic pain in the general …

Pharmacological management of chronic neuropathic pain: revised consensus statement from the Canadian Pain Society

DE Moulin, A Boulanger, AJ Clark… - Pain Research and …, 2014 - Wiley Online Library
BACKGROUND: Neuropathic pain (NeP), redefined as pain caused by a lesion or a disease
of the somatosensory system, is a disabling condition that affects approximately two million …

Pain assessment and treatment in children with significant impairment of the central nervous system

J Hauer, AJ Houtrow - Pediatrics, 2017 - publications.aap.org
Pain is a frequent and significant problem for children with impairment of the central nervous
system, with the highest frequency and severity occurring in children with the greatest …