Conspectus Polyphenols are naturally occurring compounds that are ubiquitous in plants
and display a spectrum of physical, chemical, and biological properties. For example, they …

Nanoparticles (NPs) have emerged as a powerful drug-delivery tool for cancer therapies to
enhance the specificity of drug actions, while reducing the systemic side effects …

The clinical application of chemotherapy is impeded by the unsatisfactory efficacy and
severe side effects. Chemodynamic therapy (CDT) has emerged as an efficient strategy for …

Surface modification with poly (ethylene glycol)(PEGylation) is an effective strategy to
improve the colloidal stability of nanoparticles (NPs) and is often used to minimize cellular …

The administration of nanoparticles (NPs) first faces the challenges of evading renal filtration
and clearance of reticuloendothelial system (RES). After that, NPs infiltrate through the …

Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a
commonly used approach for improving the efficiency of drug and gene delivery to target …

The incorporation of new modalities into chemotherapy greatly enhances the anticancer
efficacy combining the merits of each treatment, showing promising potentials in clinical …

Engineering functional nanomaterials with high therapeutic efficacy and minimum side
effects has increasingly become a promising strategy for cancer treatment. Herein, a reactive …

Tea, as a well-known medicinal beverage, has gained a widespread reputation for its
remarkable health benefits. Among various constituents in tea, tea polyphenols (TPs) stand …

Antibody-directed targeting of chemotherapeutic nanoparticles to primary human cancers
holds promise for improving efficacy and reducing off-target toxicity. However, clinical …