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Physiological principles underlying the kidney targeting of renal nanomedicines
Kidney disease affects more than 10% of the global population and is associated with
considerable morbidity and mortality, highlighting a need for new therapeutic options …
considerable morbidity and mortality, highlighting a need for new therapeutic options …
Cell and gene therapy for kidney disease
JL Peek, MH Wilson - Nature Reviews Nephrology, 2023 - nature.com
Kidney disease is a leading cause of morbidity and mortality across the globe. Current
interventions for kidney disease include dialysis and renal transplantation, which have …
interventions for kidney disease include dialysis and renal transplantation, which have …
Non-invasive molecular imaging of kidney diseases
In nephrology, differential diagnosis or assessment of disease activity largely relies on the
analysis of glomerular filtration rate, urinary sediment, proteinuria and tissue obtained …
analysis of glomerular filtration rate, urinary sediment, proteinuria and tissue obtained …
[HTML][HTML] The application of nanoparticles in diagnosis and treatment of kidney diseases
Nanomedicine is currently showing great promise for new methods of diagnosing and
treating many diseases, particularly in kidney disease and transplantation. The unique …
treating many diseases, particularly in kidney disease and transplantation. The unique …
Advanced drug delivery systems for renal disorders
Kidney disease management and treatment are currently causing a substantial global
burden. The kidneys are the most important organs in the human urinary system, selectively …
burden. The kidneys are the most important organs in the human urinary system, selectively …
Renal cell carcinoma management: a step to nano-chemoprevention
Renal cell carcinoma (RCC) is one of the most common kidney cancers, responsible for
nearly 90% of all renal malignancies. Despite the availability of many treatment strategies …
nearly 90% of all renal malignancies. Despite the availability of many treatment strategies …
Nanomedicine for combination urologic cancer immunotherapy
Y Tian, Z Liu, J Wang, L Li, F Wang, Z Zhu, X Wang - Pharmaceutics, 2023 - mdpi.com
Urologic cancers, particularly kidney, bladder, and prostate cancer, have a growing
incidence and account for about a million annual deaths worldwide. Treatments, including …
incidence and account for about a million annual deaths worldwide. Treatments, including …
Targeted nanomedicine modulating intercellular communications to arrest renal cell carcinoma progression
Renal cell carcinoma (RCC) records for 2% of all cancer assessments and mortality
worldwide, and its severity has more than doubled in the world over the last half-century …
worldwide, and its severity has more than doubled in the world over the last half-century …
Rational nanoparticle design: Optimization using insights from experiments and mathematical models
Polymeric nanoparticles are highly tunable drug delivery systems that show promise in
targeting therapeutics to specific sites within the body. Rational nanoparticle design can …
targeting therapeutics to specific sites within the body. Rational nanoparticle design can …
Intra-organ delivery of nanotherapeutics for organ transplantation
Targeted delivery of therapeutics through the use of nanoparticles (NPs) has emerged as a
promising method that increases their efficacy and reduces their side effects. NPs can be …
promising method that increases their efficacy and reduces their side effects. NPs can be …