Cells interact with their environment, communicate among themselves, track time and make
decisions through functions controlled by natural regulatory genetic circuits consisting of …

As synthetic biology permeates society, the signal processing circuits in engineered living
systems must be customized to meet practical demands. Towards this mission, novel …

Inflammatory bowel disease (IBD) is a complex chronic inflammatory disorder of the
gastrointestinal tract. Extracellular adenosine triphosphate (eATP) produced by the …

Modern genome-scale methods that identify new genes, such as proteogenomics and
ribosome profiling, have revealed, to the surprise of many, that overlap in genes, open …

Synthetic microbial consortia represent a new frontier for synthetic biology given that they
can solve more complex problems than monocultures. However, most attempts to co …

The construction of synthetic gene circuits in plants has been limited by a lack of orthogonal
and modular parts. Here, we implement a CRISPR (clustered regularly interspaced short …

Genomically minimal cells, such as JCVI-syn3. 0, offer a platform to clarify genes underlying
core physiological processes. Although this minimal cell includes genes essential for …

Many efforts have been put into engineering plants to improve crop yields and stress
tolerance and boost the bioproduction of valuable molecules. Yet, our capabilities are still …

Synthetic biology provides a new paradigm for life science research (“build to learn”) and
opens the future journey of biotechnology (“build to use”). Here, we discuss advances of …

Synthetic biology has been develo** rapidly in the last decade and is attracting increasing
attention from many plant biologists. The production of high-value plant-specific secondary …