Principles and applications of nucleic acid strand displacement reactions

FC Simmel, B Yurke, HR Singh - Chemical reviews, 2019 - ACS Publications
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …

Dynamic DNA nanotechnology using strand-displacement reactions

DY Zhang, G Seelig - Nature chemistry, 2011 - nature.com
The specificity and predictability of Watson–Crick base pairing make DNA a powerful and
versatile material for engineering at the nanoscale. This has enabled the construction of a …

Scaling up digital circuit computation with DNA strand displacement cascades

L Qian, E Winfree - science, 2011 - science.org
To construct sophisticated biochemical circuits from scratch, one needs to understand how
simple the building blocks can be and how robustly such circuits can scale up. Using a …

Large-scale de novo DNA synthesis: technologies and applications

S Kosuri, GM Church - Nature methods, 2014 - nature.com
For over 60 years, the synthetic production of new DNA sequences has helped researchers
understand and engineer biology. Here we summarize methods and caveats for the de novo …

NNV: the neural network verification tool for deep neural networks and learning-enabled cyber-physical systems

HD Tran, X Yang, D Manzanas Lopez, P Musau… - … on Computer Aided …, 2020 - Springer
This paper presents the Neural Network Verification (NNV) software tool, a set-based
verification framework for deep neural networks (DNNs) and learning-enabled cyber …

Neural network computation with DNA strand displacement cascades

L Qian, E Winfree, J Bruck - nature, 2011 - nature.com
The impressive capabilities of the mammalian brain—ranging from perception, pattern
recognition and memory formation to decision making and motor activity control—have …

Materials learning from life: concepts for active, adaptive and autonomous molecular systems

R Merindol, A Walther - Chemical Society Reviews, 2017 - pubs.rsc.org
Bioinspired out-of-equilibrium systems will set the scene for the next generation of molecular
materials with active, adaptive, autonomous, emergent and intelligent behavior. Indeed life …

[HTML][HTML] From cascaded catalytic nucleic acids to enzyme–DNA nanostructures: controlling reactivity, sensing, logic operations, and assembly of complex structures

F Wang, CH Lu, I Willner - Chemical reviews, 2014 - ACS Publications
DNA is one of the most fascinating biopolymers. Besides its central role as carrier of genetic
information and translation of the genetic code into proteins, DNA holds great promise as a …

Programming nanoparticle valence bonds with single-stranded DNA encoders

G Yao, J Li, Q Li, X Chen, X Liu, F Wang, Z Qu, Z Ge… - Nature materials, 2020 - nature.com
Nature has evolved strategies to encode information within a single biopolymer to program
biomolecular interactions with characteristic stoichiometry, orthogonality and …

On the biophysics and kinetics of toehold-mediated DNA strand displacement

N Srinivas, TE Ouldridge, P Šulc… - Nucleic acids …, 2013 - academic.oup.com
Dynamic DNA nanotechnology often uses toehold-mediated strand displacement for
controlling reaction kinetics. Although the dependence of strand displacement kinetics on …