Since the first attempt to administer insulin orally in humans more than 90 years ago, the oral
delivery of macromolecular drugs (> 1000 g/mol) has been rather disappointing. Although …

For decades, the development of peptides as potential drugs was aimed solely at peptides
with the highest affinity, receptor selectivity, or stability against enzymatic degradation …

Abstract Empirical Bayes (“post hoc”) estimates (EBEs) of ηs provide modelers with
diagnostics: the EBEs themselves, individual prediction (IPRED), and residual errors …

Purpose: To compare the performance of the standard lag time model (LAG model) with the
performance of an analytical solution of the transit compartment model (TRANSIT model) in …

Traumatic brain injury (TBI) is a significant cause of morbidity and mortality in many age
groups. Neuroendocrine dysfunction has been recognized as a consequence of TBI and …

This article describes the population pharmacokinetics of rifampin in South African
pulmonary tuberculosis patients. Three datasets containing 2,913 rifampin plasma …

The pharmacokinetics and pharmacodynamics of drugs are different in adult and paediatric
populations, the latter being particularly heterogeneous. These differences in …

Alarm interventions for nocturnal enuresis in children - Caldwell, PHY - 2020 | Cochrane
Library Skip to Content Cookies Our site uses cookies to improve your experience. You can …

Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs,
Second Edition addresses the pivotal issues relating to translational science, including …

Desmopressin is a synthetic analogue of the natural antidiuretic hormone arginine
vasopressin. Over the years, it has been clinically used to manage nocturnal polyuria in …