Parkinson's disease (PD) is the second most common neurodegenerative disease, and its
hallmark pathological features are the loss of dopaminergic (DA) neurons in the midbrain …

Autoimmune neurology is a rapidly expanding field driven by the discovery of neuroglial
autoantibodies and encompassing a myriad of conditions affecting every level of the …

Abstract Aquaporin-4 (AQP4) is essential for normal functioning of the brain's glymphatic
system. Impaired glymphatic function is associated with neuroinflammation. Recent clinical …

Inflammatory stimuli administered to humans and laboratory animals affect mesolimbic and
nigrostriatal dopaminergic pathways in association with impaired motivation and motor …

Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous
system, commonly causing sensory disturbances, motor weakness, impaired gait …

Objective: Investigate the MHC-I pathway in microglia as it relates to aging and AD and
isolate disease associated microglia to understand the role of this pathway and microglial …