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Short-chain fatty-acid-producing bacteria: key components of the human gut microbiota
Short-chain fatty acids (SCFAs) play a key role in health and disease, as they regulate gut
homeostasis and their deficiency is involved in the pathogenesis of several disorders …
homeostasis and their deficiency is involved in the pathogenesis of several disorders …
Butyrate producers,“The Sentinel of Gut”: Their intestinal significance with and beyond butyrate, and prospective use as microbial therapeutics
Gut-microbial butyrate is a short-chain fatty acid (SCFA) of significant physiological
importance than the other major SCFAs (acetate and propionate). Most butyrate producers …
importance than the other major SCFAs (acetate and propionate). Most butyrate producers …
Short-chain fatty acids in diseases
D Zhang, YP Jian, YN Zhang, Y Li, LT Gu… - Cell Communication and …, 2023 - Springer
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation
of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate …
of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate …
Ruminococcus gnavus: friend or foe for human health
EH Crost, E Coletto, A Bell… - FEMS microbiology …, 2023 - academic.oup.com
Ruminococcus gnavus was first identified in 1974 as a strict anaerobe in the gut of healthy
individuals, and for several decades, its study has been limited to specific enzymes or …
individuals, and for several decades, its study has been limited to specific enzymes or …
Gut-microbiota-derived metabolites maintain gut and systemic immune homeostasis
J Wang, N Zhu, X Su, Y Gao, R Yang - Cells, 2023 - mdpi.com
The gut microbiota, including bacteria, archaea, fungi, viruses and phages, inhabits the
gastrointestinal tract. This commensal microbiota can contribute to the regulation of host …
gastrointestinal tract. This commensal microbiota can contribute to the regulation of host …
[HTML][HTML] Molecular mechanisms and therapeutic targets for diabetic kidney disease
Diabetic kidney disease has a high global disease burden and substantially increases the
risk of kidney failure and cardiovascular events. Despite treatment, there is substantial …
risk of kidney failure and cardiovascular events. Despite treatment, there is substantial …
Microbiome-based therapeutics
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
Regulation of short-chain fatty acids in the immune system
XF Liu, JH Shao, YT Liao, LN Wang, Y Jia… - Frontiers in …, 2023 - frontiersin.org
A growing body of research suggests that short-chain fatty acids (SCFAs), metabolites
produced by intestinal symbiotic bacteria that ferment dietary fibers (DFs), play a crucial role …
produced by intestinal symbiotic bacteria that ferment dietary fibers (DFs), play a crucial role …
The role of short-chain fatty acids in the interplay between gut microbiota and diet in cardio-metabolic health
The gut microbiota plays an important role in cardio-metabolic diseases with diet being
among the strongest modulators of gut microbiota composition and function. Resistant …
among the strongest modulators of gut microbiota composition and function. Resistant …
Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases
The gut microbiota has a critical role in the maintenance of immune homeostasis. Alterations
in the intestinal microbiota and gut microbiota-derived metabolites have been recognized in …
in the intestinal microbiota and gut microbiota-derived metabolites have been recognized in …