Evolution of antibody immunity to SARS-CoV-2

C Gaebler, Z Wang, JCC Lorenzi, F Muecksch, S Finkin… - Nature, 2021‏ - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected 78 million
individuals and is responsible for over 1.7 million deaths to date. Infection is associated with …

Gastrointestinal manifestations of SARS-CoV-2: transmission, pathogenesis, immunomodulation, microflora dysbiosis, and clinical implications

SSK Durairajan, AK Singh, UB Saravanan… - Viruses, 2023‏ - mdpi.com
The clinical manifestation of COVID-19, caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), in the respiratory system of humans is widely recognized …

Gastroenterological and hepatic manifestations of patients with COVID-19, prevalence, mortality by country, and intensive care admission rate: systematic review and …

M Shehab, F Alrashed, S Shuaibi… - BMJ open …, 2021‏ - bmjopengastro.bmj.com
Background and aims Patients infected with the SARS-CoV-2 usually report fever and
respiratory symptoms. However, multiple gastrointestinal (GI) manifestations such as …

Plasma markers of disrupted gut permeability in severe COVID-19 patients

LB Giron, H Dweep, X Yin, H Wang, M Damra… - Frontiers in …, 2021‏ - frontiersin.org
A disruption of the crosstalk between the gut and the lung has been implicated as a driver of
severity during respiratory-related diseases. Lung injury causes systemic inflammation …

Enteric coronavirus infection and treatment modeled with an immunocompetent human intestine-on-a-chip

A Bein, S Kim, G Goyal, W Cao, C Fadel… - Frontiers in …, 2021‏ - frontiersin.org
Many patients infected with coronaviruses, such as SARS-CoV-2 and NL63 that use ACE2
receptors to infect cells, exhibit gastrointestinal symptoms and viral proteins are found in the …

New insights into the physiopathology of COVID-19: SARS-CoV-2-associated gastrointestinal illness

CA Devaux, JC Lagier, D Raoult - Frontiers in medicine, 2021‏ - frontiersin.org
Although SARS-CoV-2 is considered a lung-tropic virus that infects the respiratory tract
through binding to the ACE2 cell-surface molecules present on alveolar lungs epithelial …

Calprotectin, an emerging biomarker of interest in COVID-19: a systematic review and meta-analysis

R Udeh, S Advani, LG de Guadiana Romualdo… - Journal of clinical …, 2021‏ - mdpi.com
COVID-19 has been shown to present with varied clinical course, necessitating a need for
more specific diagnostic tools that could identify severe cases and predict outcomes during …

Elevated fecal and serum calprotectin in COVID-19 are not consistent with gastrointestinal symptoms

H Shokri-Afra, A Alikhani, B Moradipoodeh… - Scientific reports, 2021‏ - nature.com
Intestinal epithelial cell damage caused by SARS-CoV-2 infection was thought to be
associated with gastrointestinal symptoms and decreased fecal consistency. The …

The gut microbiome: a missing link in understanding the gastrointestinal manifestations of COVID-19?

EF Brooks, AS Bhatt - Molecular Case Studies, 2021‏ - molecularcasestudies.cshlp.org
Coronavirus disease 2019 (COVID-19), which is caused by infection with SARS-CoV-2,
presents with a broad constellation of both respiratory and nonrespiratory symptoms …

Pathogenesis and mechanism of gastrointestinal infection with COVID-19

H Zhang, B Shao, Q Dang, Z Chen, Q Zhou… - Frontiers in …, 2021‏ - frontiersin.org
As a new infectious disease, COVID-19 is spread through the respiratory tract in most cases.
Its source and pathological mechanism are not clear. The most common clinical feature is …