The gut microbiota as a target to control hyperuricemia pathogenesis: Potential mechanisms and therapeutic strategies

J Wang, Y Chen, H Zhong, F Chen… - Critical Reviews in …, 2022 - Taylor & Francis
Hyperuricemia (HUA) is a metabolic disorder caused by abnormal uric acid (UA)
metabolism, which is a complex physiological process involving multiple organs (liver …

Natural compounds with xanthine oxidase inhibitory activity: A review

A Mehmood, M Ishaq, L Zhao, B Safdar… - Chemical biology & …, 2019 - Wiley Online Library
Hyperuricemia (HUA), a disease due to an elevation of body uric acid level and responsible
for various diseases such as gout, cardiovascular disorders, and renal failure, is a major …

Chlorogenic acid supplementation ameliorates hyperuricemia, relieves renal inflammation, and modulates intestinal homeostasis

X Zhou, B Zhang, X Zhao, Y Lin, J Wang, X Wang… - Food & Function, 2021 - pubs.rsc.org
Hyperuricemia (HUA) is induced by abnormal purine metabolism and elevated serum uric
acid (UA) concentrations, and it is often accompanied by inflammatory responses and …

Limosilactobacillus fermentum JL-3 isolated from “Jiangshui” ameliorates hyperuricemia by degrading uric acid

Y Wu, Z Ye, P Feng, R Li, X Chen, X Tian, R Han… - Gut …, 2021 - Taylor & Francis
Recent studies into the beneficial effects of fermented foods have shown that this class of
foods are effective in managing hyperuricemia and gout. In this study, the uric acid (UA) …

Impact of ultrasound and conventional extraction techniques on bioactive compounds and biological activities of blue butterfly pea flower (Clitoria ternatea L.)

A Mehmood, M Ishaq, L Zhao, S Yaqoob… - Ultrasonics …, 2019 - Elsevier
The present study was conducted to evaluate the influence of ultrasound on bioactive
compounds and biological activities of blue butterfly pea flower (Clitoria ternatea L.). For this …

Bioactive compounds from plant-based functional foods: a promising choice for the prevention and management of hyperuricemia

LL Jiang, X Gong, MY Ji, CC Wang, JH Wang, MH Li - Foods, 2020 - mdpi.com
Hyperuricemia is a common metabolic disease that is caused by high serum uric acid levels.
It is considered to be closely associated with the development of many chronic diseases …

Anti-inflammatory and anti-hyperuricemic effects of chrysin on a high fructose corn syrup-induced hyperuricemia rat model via the amelioration of urate transporters …

YH Chang, YF Chiang, HY Chen, YJ Huang, KL Wang… - Antioxidants, 2021 - mdpi.com
Hyperuricemia is the main cause of gout and involved in the occurrence of many other
diseases such as hyperlipidemia and hypertension correlated with metabolic disorders …

In vitro inhibitory effects of polyphenols from Tartary buckwheat on xanthine oxidase: Identification, inhibitory activity, and action mechanism

J Li, Y Gong, J Li, L Fan - Food Chemistry, 2022 - Elsevier
The xanthine oxidase (XO) inhibitory activity is an important way to evaluate the anti-
hyperuricemia effect of natural products. In the present work, the XO inhibitory effect of …

Identification, inhibitory mechanism and transepithelial transport of xanthine oxidase inhibitory peptides from whey protein after simulated gastrointestinal digestion …

X Qi, H Chen, K Guan, Y Sun, R Wang, Y Ma - Food Research International, 2022 - Elsevier
In the present study, xanthine oxidase (XO) inhibitory peptides were identified from peptides
that survived in whey protein isolate (WPI) simulated gastrointestinal digestion and passed …

Dietary anthocyanins as natural phytochemicals for regulating hyperuricemia: Proposed intestinal flora, key enzyme activity, and anti-inflammatory pathways

S Lv, W Jia, R Zhang, L Zhang - Trends in Food Science & Technology, 2024 - Elsevier
Background Excessive intake of high-purine foods can lead to elevated levels of uric acid in
the blood, resulting in the occurrence of hyperuricemia, seriously affecting human health …