G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the
physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from …

Mesocotical dopamine (DA) inputs to the prefrontal cortex (PFC) play a crtical role in normal
cognitive process and neuropsychiatic pathologies. This DA input regulates aspects of …

The D1-like (D1, D5) and D2-like (D2, D3, D4) classes of dopamine receptors each has
shared signaling properties that contribute to the definition of the receptor class, although …

An important conceptual advance in the past decade has been the understanding that the
process of drug addiction shares striking commonalities with neural plasticity associated …

N-Methyl-D-aspartate ionotropic glutamate receptors (NMDARs) play key roles in
synaptogenesis, synaptic maturation, long-term plasticity, neuronal network activity, and …

A large body of phenomenological evidence implicates abnormal connectivity of brain
macrocircuitry and microcircuitry in schizophrenia. Recent discoveries of susceptibility …

Dopamine (DA) receptor, a significant G protein-coupled receptor, is classified into two
families: D1-like (D1 and D5) and D2-like (D2, D3, and D4) receptor families, with further …

The drugs of abuse, methamphetamine and MDMA, produce long‐term decreases in
markers of biogenic amine neurotransmission. These decreases have been traditionally …

Direct interactions between receptors at the neuronal surface have long been proposed to
tune signaling cascades and neuronal communication in health and disease. Yet, the lack of …

Although animals cannot be used to study complex human behaviour such as language,
they do have similar basic functions. In fact, human disorders that have animal models are …