Tumor hypoxia is a well-established biological phenomenon that affects the curability of
solid tumors, regardless of treatment modality. Especially for head and neck cancer patients …

Reduced oxygen levels (hypoxia) is one of the most important factors influencing clinical
outcome after radiotherapy. This is primarily because hypoxic cells are resistant to radiation …

Hypoxia is known to be a poor prognostic indicator for nearly all solid tumours and also is
predictive of treatment failure for radiotherapy, chemotherapy, surgery and targeted …

Our understanding of tumour biology has evolved over the past decades and cancer is now
viewed as a complex ecosystem with interactions between various cellular and non-cellular …

Tumour hypoxia is a known and extensively researched phenomenon that occurs in both
solid and haematological malignancies. As cancer cells proliferate, demand for oxygen can …

The use of modern MRI technology in radiotherapy is fast growing. MRI is entering all facets
of radiotherapy. This review will start with a very short overview of the newest developments …

Purpose: Tumor hypoxia is an important determinant of outcome in many human
malignancies and is associated with treatment resistance and metastases. The aim of this …

Hypoxia, a condition of insufficient O 2 to support metabolism, occurs when the vascular
supply is interrupted, as in stroke or myocardial infarction, or when a tumor outgrows its …

Hypoxia was identified as a microenvironmental component of solid tumours over 60 years
ago and was immediately recognised as a potential barrier to therapy through the reliance of …

The clinical complications of atherosclerosis are caused by thrombus formation, which in
turn results from rupture of an unstable atherosclerotic plaque. The formation of …