This article emphasizes on the importance of benzofuran as a biologically relevant
heterocycle. It covers most of the physiologically as well as medicinally important …

The aim of this review was to discuss an overview of type 2 diabetes; biology of PTP1B; role
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …

There is a growing interest in the use of small molecules as chemical probes in parallel to
classical genomic tools (gene expression, gene profiling, gene knockouts, and siRNA-based …

We report the synthesis of new series of heterocyclic systems eugenol 1 derivatives by the
mixed condensation reaction of 1, 3-dipolar azide and the oxide of p-chlorophenylnitrile on …

Protein tyrosine phosphatases (PTPs) are considered to be involved in the etiology of
diabetes mellitus, neural diseases such as Alzheimer's and Parkinson's disease, regulation …

Protein tyrosine phosphatases (PTPs) play a critical role in physiological signaling pathways
by controlling the level of tyrosine phosphorylation. The past decade has seen a vast …

The reaction of 2-oxo-N-arylpropanehydrazonoyl chlorides 3a–e with 3-methyl-2-
benzofurancarboxylic acid hydrazide (7) furnished N-(aryl) propanehydrazonoyl chlorides …

Abstract A base‐promoted [3+ 2]‐annulation of ketoxime esters and aldehydes is disclosed
for the facile and rapid synthesis of 3, 5‐disubstituted and 3, 4, 5‐trisubstituted isoxazolines …

Oxime esters as the applicable building blocks, internal oxidizing agents, and directing
groups in the synthesis of–, S-, and O-containing heterocycle scaffolds have gained great …

New thiazolylmethoxyphenyl pyrimidines (7a–g) have been conveniently synthesized with
better yields by cyclocondensing 3-(4-((2-phenylthiazol-4-yl) methoxy) phenyl)-1-(4 …