A substantial body of literature has provided evidence for the role of gut microbiota in
metabolic diseases including type 2 diabetes. However, reports vary regarding the …

Understanding how dietary nutrients modulate the gut microbiome is of great interest for the
development of food products and eating patterns for combatting the global burden of non …

A growing body of evidence suggests that dysbiosis of the human gut microbiota is
associated with neurodegenerative diseases like Alzheimer's disease (AD) via …

In the present study, we characterized the distinctive signatures of the gut microbiota (GM)
from overweight/obese patients (OB), and normal-weight controls (NW), both of Sardinian …

Background Bioactive lipids produced by human cells or by the gut microbiota might play an
important role in health and disease. Dietary intakes are key determinants of the gut …

Objective Tryptophan can be catabolised to various metabolites through host kynurenine
and microbial indole pathways. We aimed to examine relationships of host and microbial …

Researchers have discovered associations between elements of the intestinal microbiome
(including specific microbes, signaling pathways, and microbiota-related metabolites) and …

Gut microbiota has attracted widespread attention due to its crucial role in disease
pathophysiology, including type 2 diabetes mellitus (T2DM). Metabolites and bacterial …

The tryptophan–kynurenine pathway (Trp–KYN) is the major route for tryptophan conversion
in the brain and in the periphery. Kynurenines display a wide range of biological actions …

Diabetes mellitus is a significant clinical and therapeutic problem because it can lead to
serious long-term complications. Its pathogenesis is not fully understood, but there are …