Cardiac natriuretic peptides (NPs), atrial NP (ANP) and B-type NP (BNP) are true hormones
produced and released by cardiomyocytes, exerting several systemic effects. Together with …

BACKGROUND Interest in cardiovascular biomarkers in primary prevention has increased
dramatically in the past decade. This increase has been fueled by an improved …

2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American
College of Cardiology Foundation/American Heart Association Task Force on Practice …

1.1. Methodology and Evidence Review The recommendations listed in this document are,
whenever possible, evidence based. An extensive evidence review was conducted through …

Background Predicting mortality is important in patients with heart failure (HF). However,
current strategies for predicting risk are only modestly successful, likely because they are …

Background Predicting hospital mortality risk is essential for the care of heart failure patients,
especially for those in intensive care units. Methods Using a novel machine learning …

The concept of the heart as an endocrine organ emerged with the discovery of the atrial
natriuretic peptide (ANP) by de Bold et al.(1) in 1981, followed later by the discovery of B …

BACKGROUND High-sensitivity cardiac troponin (hs-cTn) assays are now available that can
detect measurable troponin in significantly more individuals in the general population than …

The goal of this research is to develop a reliable decision-support system for the survival
prediction of heart failure patients by utilizing their clinical records and laboratory test results …

We sought to investigate the role of aldosterone as a mediator of disease and its relationship
with the counter-regulatory natriuretic peptide (NP) system. We measured plasma …