Chitosan-based drug delivery systems: from synthesis strategy to osteomyelitis treatment–a review
F Tao, S Ma, H Tao, L **, Y Luo, J Zheng, W **ang… - Carbohydrate …, 2021 - Elsevier
Osteomyelitis is a complex disease in orthopedics mainly caused by bacterial pathogens
invading bone or bone marrow. The treatment of osteomyelitis is highly difficult and it is a …
invading bone or bone marrow. The treatment of osteomyelitis is highly difficult and it is a …
Mechanisms of Antibiotic Failure During Staphylococcus aureus Osteomyelitis
BD Gimza, JE Cassat - Frontiers in immunology, 2021 - frontiersin.org
Staphylococcus aureus is a highly successful Gram-positive pathogen capable of causing
both superficial and invasive, life-threatening diseases. Of the invasive disease …
both superficial and invasive, life-threatening diseases. Of the invasive disease …
Recapitulating antioxidant and antibacterial compounds into a package for tissue regeneration: dual function materials with synergistic effect
Oxidative damage and infection can prevent or delay tissue repair. Moreover, infection
reinforces reactive oxygen species (ROS) formation, which makes the wound's condition …
reinforces reactive oxygen species (ROS) formation, which makes the wound's condition …
Iodine Immobilized Metal–Organic Framework for NIR‐Triggered Antibacterial Therapy on Orthopedic Implants
W Teng, Z Zhang, Y Wang, Y Ye, E Yinwang, A Liu… - Small, 2021 - Wiley Online Library
Iodine has been known as an effective disinfectant with broad‐spectrum antimicrobial
potency yet without drug resistance risk when used in clinic. However, the exploration of …
potency yet without drug resistance risk when used in clinic. However, the exploration of …
Interface Polarization Strengthened Microwave Catalysis of MoS2/FeS/Rhein for the Therapy of Bacteria‐Infected Osteomyelitis
L **, X Liu, Y Zheng, Z Li, Y Zhang… - Advanced Functional …, 2022 - Wiley Online Library
Abstract Staphylococcus aureus (S. aureus)‐induced osteomyelitis is fatal to patients, even
leading to death without timely debridement processing, which is difficult to be treated by …
leading to death without timely debridement processing, which is difficult to be treated by …
A multifunctional scaffold for bone infection treatment by delivery of microRNA therapeutics combined with antimicrobial nanoparticles
Treating bone infections and ensuring bone repair is one of the greatest global challenges
of modern orthopedics, made complex by antimicrobial resistance (AMR) risks due to long …
of modern orthopedics, made complex by antimicrobial resistance (AMR) risks due to long …
[HTML][HTML] Hematoma-like dynamic hydrogelation through natural glycopeptide molecular recognition for infected bone fracture repair
S Wang, W He, H Wang, D Liu, M Wang, H Yang… - Bioactive Materials, 2023 - Elsevier
Infected bone fractures remain a major clinical challenge for orthopedic surgeons. From a
tissue regeneration perspective, biomaterial scaffolds with antibacterial and osteoinductive …
tissue regeneration perspective, biomaterial scaffolds with antibacterial and osteoinductive …
Magnetic Composite Rapidly Treats Staphylococcus aureus‐Infected Osteomyelitis through Microwave Strengthened Thermal Effects and Reactive Oxygen Species
It is difficult to effectively treat bacterial osteomyelitis using photothermal therapy or
photodynamic therapy due to poor penetration of light. Here, a microwave (MW)‐excited …
photodynamic therapy due to poor penetration of light. Here, a microwave (MW)‐excited …
Enhancing Microwave Dynamic Effects via Surface States of Ultrasmall 2D MOF Triggered by Interface Confinement for Antibiotics‐Free Therapy
Microwave (MV)‐trigged dynamic therapy based on MV‐responsive materials is promising
for treating deep infection diseases that cannot be effectively treated by antibiotics, like life …
for treating deep infection diseases that cannot be effectively treated by antibiotics, like life …
[HTML][HTML] In situ sprayed hydrogels containing resiquimod-loaded liposomes reduce chronic osteomyelitis recurrence by intracellular bacteria clearance
L Tian, Z Tan, Y Yang, S Liu, Q Yang, Y Tu, J Chen… - Acta Biomaterialia, 2023 - Elsevier
At present, surgical debridement and systematic administration of antibiotics represent the
mainstay of treatment for chronic osteomyelitis. However, it is now understood that …
mainstay of treatment for chronic osteomyelitis. However, it is now understood that …