The highly disagreeable sensation of pain results from an extraordinarily complex and
interactive series of mechanisms integrated at all levels of the neuroaxis, from the periphery …

Peripheral and central mechanisms of cutaneous hyperalgesia - ScienceDirect Skip to main
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The third edition of this monograph continues to have the goal of providing an overview of
current thought about the spinal cord mechanisms that are responsible for sensory …

Increases in neuronal activity in response to tissue injury lead to changes in gene
expression and prolonged changes in the nervous system. These functional changes …

Burstein, Rami, Hiroyoshi Yamamura, Amy Malick, and Andrew M. Strassman. Chemical
stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain …

Multireceptive neurones are found in the spinal dorsal horn and may be projection neurones
and/or interneurones for polysynaptic reflexes. The cutaneous receptive field of a …

The involvement of NMDA receptors in rats with peripheral inflammation and hyperalgesia
was evaluated by administration of the non-competitive NMDA receptor antagonist, MK-801 …

To test the hypothesis that painful stimuli to skeletal muscle lead to a widespread unmasking
of synaptic connections in dorsal horn neurons, intramuscular injections of bradykinin (BKN) …

In this paper we review the current neurophysiological models of touch-evoked pain and
present a new proposal that addresses the mechanisms of allodynia. The new model is …

Publisher Summary This chapter discusses evolutionary aspects of injury-related behavior,
and examines behavioral, physiological, and molecular aspects of potentially adaptive …