Chronic Inflammation in tumor microenvironments is not only associated with various stages
of tumor development, but also has significant impacts on tumor immunity and …

Prostate cancer is a highly prevalent form of cancer that is usually slow-develo** and
benign. Due to its high prevalence, it is, however, still the second most common cause of …

Purpose: Despite significant benefit for other cancer subtypes, immune checkpoint blockade
(ICB) therapy has not yet been shown to significantly improve outcomes for men with …

Inflammasomes are the central processing units (CPUs) responsible for decoding and
integrating signals of foreignness, damage, danger, and distress released by pathogens …

Obesity is a weight-related disorder characterized by excessive adipose tissue growth and
dysfunction which leads to the onset of a systemic chronic low-grade inflammatory state …

Although keratinocytes are relatively resistant to ultraviolet radiation (UVR) induced
damage, repeated UVR exposure result in accumulated DNA mutations that can lead to …

Prostate cancer treatment is currently based on surgical removal, radiotherapy, and
hormone therapy. In recent years, another therapeutic method has emerged …

Tumour necrosis factor (TNF) is a pleiotropic cytokine with dual roles in cancer biology
including prostate cancer (PCa). On the one hand, there is evidence that it stimulates tumour …

The zeolitic imidazolate framework (ZIF) is one of the most explored metal–organic-
framework-based systems for nucleic acid delivery to cancer cells. Current nucleic acid …

Myeloid-derived suppressor cells (MDSCs) are major immunosuppressive cells that lead to
T cell defects in cancer. IL-18 is important in inflammatory and immune responses. IL-18 has …