EMT transition states during tumor progression and metastasis

I Pastushenko, C Blanpain - Trends in cell biology, 2019 - cell.com
Epithelial–mesenchymal transition (EMT) is a process in which epithelial cells acquire
mesenchymal features. In cancer, EMT is associated with tumor initiation, invasion …

Hybrid epithelial/mesenchymal phenotypes promote metastasis and therapy resistance across carcinomas

MK Jolly, JA Somarelli, M Sheth, A Biddle… - Pharmacology & …, 2019 - Elsevier
Cancer metastasis and therapy resistance are the major unsolved clinical challenges, and
account for nearly all cancer-related deaths. Both metastasis and therapy resistance are …

EMT and MET: necessary or permissive for metastasis?

MK Jolly, KE Ware, S Gilja, JA Somarelli… - Molecular …, 2017 - Wiley Online Library
Epithelial‐to‐mesenchymal transition (EMT) and its reverse mesenchymal‐to‐epithelial
transition (MET) have been suggested to play crucial roles in metastatic dissemination of …

Inflammatory breast cancer: a model for investigating cluster-based dissemination

MK Jolly, M Boareto, BG Debeb, N Aceto… - NPJ breast …, 2017 - nature.com
Metastases claim more than 90% of cancer-related patient deaths and are usually seeded
by a subset of circulating tumor cells shed off from the primary tumor. In circulation …

Primary sarcoma of the cervix: an analysis of patient and tumor characteristics, treatment patterns, and outcomes

A Albert, A Lee, R Allbright… - Journal of gynecologic …, 2019 - pmc.ncbi.nlm.nih.gov
Objective Primary sarcoma of the cervix is rare and is associated with worse outcomes as
compared to other histologies. The purpose of this study was to identify national treatment …

Uterine carcinosarcoma: A case report and literature review

A Kord, B Rabiee, I Elbaz Younes… - Case Reports in …, 2020 - Wiley Online Library
Uterine carcinosarcomas are rare and extremely aggressive undifferentiated carcinomas
which include both carcinomatous and sarcomatous elements. A 52‐year‐old female …

Pancreatic carcinosarcoma clinical outcome analysis of the National Cancer Institute database

A Alhatem, PL Quinn, W **a, RJ Chokshi - Journal of Surgical Research, 2021 - Elsevier
Background Pancreatic carcinosarcomas (PCS) are rare aggressive biphasic malignancies
with a poor prognosis. We aimed to improve the understanding of PCS by analyzing …

HDAC inhibition induces cell cycle arrest and mesenchymal-epithelial transition in a novel pleural-effusion derived uterine carcinosarcoma cell line

P Stockhammer, Ö Okumus, L Hegedus… - Pathology and …, 2021 - por-journal.com
Objective: Uterine carcinosarcoma (UCS) is a rare but highly aggressive malignancy with
biphasic growth pattern. This morphology can be attributed to epithelial-mesenchymal …

Biphasic malignant tumours of the abdominal cavity

LM Almond, AT Warfield, A Desai, D Gourevitch… - International Journal of …, 2017 - Springer
Carcinosarcomas (CS) are uncommon, highly aggressive, biphasic tumours consisting of
both sarcomatous and carcinomatous elements. They appear to originate from a common …

Locally advanced carcinosarcoma of the pancreas

SA Still, CR Becerra, SE Clement-Kruzel… - Baylor University …, 2018 - Taylor & Francis
Carcinosarcoma is a rare subtype of pancreatic neoplasm including both carcinomatous and
sarcomatous components. Fewer than 30 cases have been reported to the Surveillance …