Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Functional chromopeptide nanoarchitectonics: Molecular design, self-assembly and biological applications

R Chang, L Zhao, R **ng, J Li, X Yan - Chemical Society Reviews, 2023 - pubs.rsc.org
Chromoproteins are a class of delicate natural compounds that elegantly complex
photosensitive species with proteins and play a central role in important life processes, such …

Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy

B Ji, M Wei, B Yang - Theranostics, 2022 - pmc.ncbi.nlm.nih.gov
Cancer immunotherapy has made tremendous clinical progress in advanced-stage
malignancies. However, patients with various tumors exhibit a low response rate to …

Mito‐bomb: targeting mitochondria for cancer therapy

X Guo, N Yang, W Ji, H Zhang, X Dong… - Advanced …, 2021 - Wiley Online Library
Cancer has been one of the most common life‐threatening diseases for a long time.
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …

Engineered exosomes from different sources for cancer-targeted therapy

M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - Signal transduction and …, 2023 - nature.com
Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …

Microenvironment‐responsive prodrug‐induced pyroptosis boosts cancer immunotherapy

Y **ao, T Zhang, X Ma, QC Yang, LL Yang… - Advanced …, 2021 - Wiley Online Library
The absence of tumor antigens leads to a low response rate, which represents a major
challenge in immune checkpoint blockade (ICB) therapy. Pyroptosis, which releases tumor …

Mitochondrial adaptation in cancer drug resistance: prevalence, mechanisms, and management

P **, J Jiang, L Zhou, Z Huang, EC Nice… - Journal of hematology & …, 2022 - Springer
Drug resistance represents a major obstacle in cancer management, and the mechanisms
underlying stress adaptation of cancer cells in response to therapy-induced hostile …

Solutions to the drawbacks of photothermal and photodynamic cancer therapy

X Deng, Z Shao, Y Zhao - Advanced science, 2021 - Wiley Online Library
Phototherapy such as photothermal therapy and photodynamic therapy in cancer treatment
has been developed quickly over the past few years for its noninvasive nature and high …

Engineering of BODIPY-based theranostics for cancer therapy

Z Mao, JH Kim, J Lee, H **ong, F Zhang… - Coordination Chemistry …, 2023 - Elsevier
In recent years, BODIPY-based theranostics have increasingly been used in cancer therapy
and have achieved significant success. According to photochemical theories, the optical …

Organelle-targeted photosensitizers for precision photodynamic therapy

R Wang, X Li, J Yoon - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Subcellular organelles are the cornerstones of cells, and destroying them will cause cell
dysfunction and even death. Therefore, realizing precise organelle targeting of …